Clinical Genome Sequencing

Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing.

Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine.

• Features contributions from leading international researchers and practitioners versed in the psychosocial dimensions of genomic medicine implementation
• Presents clinical case studies that support concept illustration, making this an invaluable reference for students, researchers, and clinicians looking for practical guidance in this important and multifaceted topic area
• Details the current state of genomic testing, expectations of genome sequencing, patient consent, patient responses to sequencing data, uncertainties in genome sequencing, direct-to-consumer genome sequencing, and more

Inhalt

1. Genetic Testing Expanded Aad Tibben and Barbara Bowles Biesecker
   2. Responses to Sequencing Information Leslie Biesecker and Barbara Bowles Biesecker
      3. Consenting Patients to Genome Sequencing Heidi Carmen Howard
         4. Judgement and Decision Making in Genome Sequencing William Klein and Barbara Bowles Biesecker
            5. Uncertainties in Genome Sequencing Barbara Bowles Biesecker and Aad Tibben
               6. Direct to Consumer Genome Sequencing Cecile Janssens
                  7. Precision (Personalized) Medicine Marc S. Williams
                     8. Genetic Counseling and Genomic Sequencing Barbara Bernhardt
                        9. Genome Sequencing in Pediatrics Candice Cornelis
                           10. Genome Sequencing in Prenatal Testing and Screening Sam Riedijk
                               11. Genome Sequencing in Psychiatric Disorders Christian Bouwkamp
                                   12. Ethical Issues in Genome Sequencing Guido de Wert
                                       13. Summary of Key Areas for Research *Barbara Bowles Biesecker and Aad Tibben *