In keeping with the style of the Handbook of Modern Biophysics, this fourth volume, Application of Near-Infrared Spectroscopy in Biomedicine, balances the need for physical science/mathematics formalism with a demand for biomedical perspectives. Each chapter divides the presentation into two major parts: the first establishes the conceptual framework and describes the instrumentation or technique, while the second illustrates current applications in addressing complex biology questions. With the additional sections on further reading, problems, and references, the interested reader can explore some chapter ideas more widely.

Auteur
Thomas Jue is a Professor in the Department of Biochemistry and Molecular Medicine at the University of California Davis. He is an internationally recognized expert in developing and applying magnetic resonance techniques to study animal as well as human physiology in vivo and has published extensively in the field of magnetic resonance spectroscopy and imaging, near-infrared spectroscopy, bioenergetics, cardiovascular regu-lation, exercise, and marine biology. As the Chair of the Biophysics Graduate Group Program at University of California Davis, he launched an initiative to establish a biophysics book series that will balance the physical-science/mathematics formalism with the biomedical perspective in order to develop an attractive education curriculum at the interface of physical science, engineering, mathematics, biology, and medicine. The Handbook of Modern Biophysics represents part of that curriculum development effort.

Contenu
Principles and Instrumentation.- Photon Migration in Tissue.- Photon Migration in NIRS Brain Imaging.- Clinical Application of NIRS.- In-Vivo NIRS and Muscle Oxidative Metabolism.- Intracellular Oxygen Dynamics Observed by NIRS during Skeletal Muscle Contraction.- Muscle Oxygen Saturation Measurements in Diving Mammals and Birds Using NIRS.- Noninvasive NMR and NIRS Measurement of Vascular and Intracellular Oxygenation In Vivo.