The Structure and Function of Nervous Tissue V6

The Structure and Function of Nervous Tissue, Volume VI: Structure IV and Physiology IV covers topics pertaining to ependyma and subependymal layer, filaments and tubules, synapse, epiphysis cerebri, excitation, macromolecules, and dopamine in the nervous system.
The book particularly discusses the main structural features and functions of the ependyma and subependymal layer. It describes the ultrastructure of the synapse, and the nonspecific changes of the central nervous system in normal and experimental materials. It also includes the molecular biology of developing mammalian brain. In addition, the ""macromolecular picture"" of nerve excitation based on accumulated experimental findings from intracellularly perfused squid giant axons is presented. Lastly, evidence pertaining to the view that dopamine plays an important role in the control of extrapyramidal (striatal) motor functions is shown.
This book will be very useful for graduate students in a variety of disciplines and for those specializing in particular aspects of nervous tissue study.

Contenu

Contributors
Preface
Contents of Other Volumes

1. Ependyma and Subependymal Layer
   I. Introduction
   II. Development
   III. General Histology
   IV. Regional Differences
   V. Function
   References
2. Filaments and Tubules in the Nervous System
   I. Introduction
   II. Microtubules
   III. Neurofilaments and Glial Filaments
   IV. Actin and Myosin in Brain
   V. Neuropathology of Fibrous Proteins
   VI. Summary
   References
3. On The Ultrastructure of the Synapse: The Synaptosome as a Morphological Tool
   I. Introduction
   II. Definition of Synaptosome
   III. Comparative Morphology
   IV. Synaptosomal Fractions
   V. Correlative Studies
   VI. Some Applications of Synaptosomal Studies
   References
4. Nonspecific Changes of the Central Nervous System in Normal and Experimental Material
   I. Introduction
   II. Abnormalities Incurred during Histologic Preparation
   III. Alterations Caused by Postmortem Trauma
   IV. Reactions of Uncertain Origin
   V. Artifactitious and Nonspecific Changes Encountered in Experimental Material
   VI. Conclusion
   References
5. The Epiphysis Cerebri
   I. Introduction
   II. Structure
   III. Function
   IV. Conclusion
   References
6. Molecular Biology of Developing Mammalian Brain
   I. Growth
   II. Metabolism of Biopolymers
   III. Myelination
   IV. Hormones
   V. Nutrition
   VI. Genetic Control of Growth
   References
7. Excitation and Macromolecules-The Squid Giant Axon
   I. Introduction
   II. Perfusion Techniques
   III. Effects of Macromolecular Reagents on Excitability
   IV. Effects of Physical Chemical Conditions on Excitability
   V. Optical Effects of Excitation
   References
8. Macromolecules and Excitation
   I. Introduction
   II. Bi-Ionic Action Potential
   III. Reactions of Macromolecules to Calcium Ion
   IV. Effects of Calcium on the Axon Membrane
   V. Effects of Proteolytic Enzymes on the Excitable Membrane
   VI. Effects of Univalent Cations on the Size of the Action Potential
   VII. Conclusions
   References
9. Dopamine and Its Physiological Significance in Brain Function
   I. Introduction
   II. Physiology and Biochemistry of Nigrostriatal Dopamine
   III. Pharmacology of Striatal Dopamine
   IV. Nigrostriatal Dopamine and Parkinsonism
   V. The Striatal Dopamine Deficiency Syndrome-Summary and Conclusions
   References
10. Brain Slices
    I. Introduction
    II. General Properties of Cerebral Cortex Slices
    III. Electrical Properties of Cerebral Cortex Slices
    IV. Ion Movement
    V. Transport of Amino Acids
    VI. Conclusions
    References
    Author Index
    Subject Index