The Biochemistry of Parasites

The Biochemistry of Parasites documents the proceedings of the Satellite Conference of the 13th Meeting of the Federation of European Biochemical Societies (FEBS) held in Jerusalem, August 1980. The conference presented the opportunity to summarize work done by parasite biochemists and introduce this field to workers in classical biochemistry.
The 45 papers in this volume are divided into two sections covering parasite biomembranes and parasite metabolism. The papers in the biomembranes section are further divided in two parts: the parasite membrane (Part I) and adherence of the parasite to host tissues (Part II). Part I is concerned with both classical and novel aspects of membrane structure and function. It includes studies on the membrane of the leishmania; the surface coat of trypanosomes; membrane function; and transport across the cell membrane. Part II covers topics such as the adherence of pathenogenic microorganisms and the importance of of carbohydrates in parasite-host adherence. The papers in the parasite metabolism section focus primarily on three groups of parasites: leishmania, malaria, and helminthes. Topics covered include the isolation and characterization of a proteolytic enzyme from Plasmodium lophurae (duck malaria); the selection and culture of malaria parasites resistant to aminopterin; and regulation of cyclic AMP metabolism in Leishmania promastigotes and amastigotes.

Contenu

Introduction
Biomembranes Section
Part I: The Parasite Membrane
Structural, Chemical and Antigenic Properties of Surface Membranes Isolated from Leishmania Donovani
Phosphomonoesterase Activities at the Surface Membrane of Leishmania Donovani Promastigotes
The Surface Membrane of Leishmania
Alterations of Human Erythrocyte Membranes, Due to Infection with Plasmodium Falciparum
The Intestine of Ascaris Suum: Some Biochemical and Physiological Characteristics
Inhibition of P. Falciparum growth In Vitro by Specific Inhibitors of Red Blood Cell Anion Transport
Externally Oriented Surface Membrane Cross-Reactive Carbohydrate Antigens in Leishmania Donovani and Trypanosoma Cruzi (Abstract)
Immunological Analysis of Membrane Proteins of Leishmania Tropica Isolates of Different Virulence (Abstract)
Lectin Analysis of the Variant Specific Antigen of T. Congolense (Abstract)
Preparative Purification of the Variant Specific Glycoproteins of Trypanosoma Congolense (Abstract)
Plasmodium Berghei: Serum Binding to Sporozoites (Abstract)
Part II: Adherence
Adherence of Pathogenic Microorganisms to the Intestinal Tract
Adherence of Mycoplasmas to Host Cell Membranes
Amebiasis: Poorly Phagocytic Substrains of Entamoeba Histolytica Show Diminished Virulence (Abstract)
Metabolism Section
Introduction
Part I: Protozoal Metabolism
The Proteases of Plasmodium: A Cathepsin D-like Enzyme from Plasmodium Lophurae
Regulation of Cyclic AMP-Metabolism in Leishmania Promastigotes and Amastigotes
The Mechanism of Aminopterin Resistance in Plasmodium Falciparum (Abstract)
Isolation and Biochemical Characterization of Malaria Parasites (P. Vinckei) (P. Falciparum) (Abstract)
A Sensitive Fluorescent Stain for Plasmodia Stages Obtained From a Percoll Gradient (Abstract)
Inhibition of P. Falciparum Growth In Vitro by a Platelet Extract (Abstract)
A New Method for the Measurement of the Influx of Chloroquine in Human Red Blood Cells (Abstract)
Affinity Chromatographie Methods for the Purification of Leishmanial Excreted Factor (Abstract)
A Possible Role for Leishmanial Excreted Factor (EF) in the Infective Process (Abstract)
Kinetoplast DNA Sequences in Leishmania (Abstract)
Toward the Primary Structure of Trypanosoma Brucei VSAfs (Abstract)
Enzymology of Energy Metabolism in Trypanosoma Cruzi Epimastigotes (Abstract)
Part II: Helminth Metabolism
Energy Generation in Parasitic Helminths
Liver fibrosis in Schistosomiasis
Pathways of Volatile Fatty Acid Production in Ascaris Lumbricoides with Particular Reference to the Synthesis of Succinyl-CoA (Abstract)
The Aerobic Energy Metabolism of the Juvenile Liver Fluke, Fasciola Hepatica (Abstract)
Part III: Immuno- and Chemotherapy
Natural and Synthetic Immunostimulants and Methylation Inhibitors as Antiparasitic Agents in Animal Models
Effect of Metrifonate and Diethylcarbamazine on Cholinesterase Activity from Onchocerca Volvulus (Abstract)
Author Index
Subject Index