The Alkaloids

The Alkaloids: Chemistry and Physiology, Volume IV contains an account of the chemistry and biosynthesis of the various classes of isoquinolines.

This book discusses the extraction and separation of the anhalonium alkaloids, other natural simple isoquinolines, and anhalonium isoquinolines. The location of the alkaloids in tissues of the cacti, monophenolic bases of the laudanosine type, and extraction of cactus alkaloids are elaborated in detail. This text also describes the several types of alkaloids such as protoberberine, aporphine, protopine, phthalideisoquinoline, and bisbenzylisoquinoline. The cularine, a-naphthaphenanthridine, erythrophleum, aconitum, and delphinium alkaloids are likewise included.

This publication is recommended for chemists, specialists, and students interested in isoquinolines.

Contenu

Preface

The Biosynthesis of Isoquinolines

Simple Isoquinoline Alkaloids

I. Introduction

II. The Anhalonium Alkaloids

III. Extraction and Separation of the Anhalonium Alkaloids

IV. The Anhalonium Isoquinolines

V. Structure and Synthesis of the Anhalonium Alkaloids

VI. Other Natural Simple Isoquinolines

VII. Pharmacology

VIII. References

Cactus Alkaloids

I. Introduction

II. Constitution and Occurrence

III. Location of the Alkaloids in Tissues of the Cacti

IV. Extraction of Cactus Alkaloids

V. References

The Benzylisoquinoline Alkaloids

I. Introduction

II. Papaverine

III. Laudanosine

IV. Monophenolic Bases of the Laudanosine Type

V. Biogenesis of the Benzylisoquinoline Alkaloids

VI. References

The Protoberberine Alkaloids

I. Introduction

II. Occurrence

III. Berberine

IV. Canadine

V. Palmatine

VI. Shobakunine

VII. Tetrahydropalmatine

VIII. Jatrorrhizine and Columbamine

IX. Corypalmine and Isocorypalmine

X. Scoulerine

XI. Sinactine

XII. Cheilanthifoline

XIII. Ophiocarpine

XIV. Capaurine and Capauridine

XV. Capaurimine

XVI. Stylopine and Coptisine

XVII. Corydaline

XVIII. Corybulbine

XIX. Isocorybulbine

XX. Thalictrifoline

XXI. Thalictricavine

XXII. Nandinine

XXIII. Worenine

XXIV. Umbellatine

XXV. Neprotine

XXVI. Thalictrine

XXVII. Coreximine

XXVIII. References

The Aporphine Alkaloids

I. Introduction

II. Glaucine

III. Glaucentrine

IV. Boldine

V. Laurotetanine

VI. N-Methyllaurotetanine

VII. Dicentrine

VIII. Actinodaphnine

IX. Domesticine

X. Nantenine

XI. Phanostenine

XII. Crebanine

XIII. Corydine

XIV. Isocorydine

XV. Corytuberine

XVI. Suaveoline

XVII. Bulbocapnine

XVIII. Laurepukine

XIX. Isothebaine

XX. Tuduranine

XXI. Laureline

XXII. Pukateine

XXIII. Anolobine

XXIV. Stephanine

XXV. Roemerine

XXVI. Anonaine

XXVII. Other Aporphines

XXVIII. References

The Protopine Alkaloids

I. Introduction

II. Occurrence

III. Cryptopine

IV. Cryptocavine

V. Protopine

VI. Allocryptopine

VII. Hunnemanine

VIII. Cryptopalmatine

IX. Corycavine

X. Corycavamine

XI. Corycavidine

XII. References

Phthalideisoquinoline Alkaloids

I. Introduction

II. Constitution

III. Syntheses

IV. Discovery, Isolation, and Properties

V. Physiology and Pharmacology

VI. References

Bisbenzylisoquinoline Alkaloids

I. Introduction

II. Alkaloids Containing One Diphenyl Ether Linkage

III. Alkaloids Containing Two Diphenyl Ether Linkages

IV. Alkaloids Containing Three Diphenyl Ether Linkages

V. References

The Cularine Alkaloids

I. Introduction

II. Cularine

III. Cularimine

IV. Cularidine

V. References

a-Naphthaphenanthridine Alkaloids

I. Introduction

II. Occurrence

III. Structure

IV. Pharmacology

V. References

The Erythrophleum Alkaloids

I. Isolation

II. Properties of the Alkaloids

III. Pharmacology

IV. References

The Aconitum and Delphinium Alkaloids

I. Introduction

II. The Chemistry of the Atisines

III. The Chemistry of the Aconitines

IV. The Monoester Alkaloids Derived from Methoxyl-Rich Amino Alcohols Analogous to the Aconines

V. "Miscellaneous" Alkaloids Isolated from Aconitum and Delphinium Species

VI. References

Author Index

Subject Index