Stereodynamics of Molecular Systems

Stereodynamics of Molecular Systems covers the proceedings of a symposium held at the State University of New York at Albany, on 23-24 April 1979. The book focuses on the stereodynamics of molecules and ions and nucleic acid structure. The contributions tackle spectroscopy, crystallography, perturbations, and electron-transfer reactions.
The selection first offers information on nuclear magnetic resonance spectroscopy chemical shifts, coupling constants, and molecular geometry, including chemical shifts, bond coupling constants, and constitutional features of nucleic acids. The book then takes a look at nuclear magnetic resonance spectroscopy stereodynamics of small molecules; nuclear magnetic resonance spectroscopy solution dynamics of polymer chains; and single crystal crystallography.
The publication evaluates the steric effects on electron-transfer reactions of sulfonamides; effects of isotopic perturbation on NMR spectra; and conformational mobility of the backbone of cyclic tripeptides. The book also discusses accessible surface areas of nucleic acids and their relation to folding, conformational transition, and protein recognition. Topics include polarity of exposed atoms, surface of DNA double helices, transfer RNA, and calculation of "static" accessible surface area.
The selection is a dependable reference for readers interested in the stereodynamics of molecules and ions and nucleic acid structure.

Contenu

Contents
Preface
President Vincent O'Leary's Welcome
Nobel Laureates Ivar Giaever and Max Perutz at the State University of New York at Albany
Inaugural Address by Nobel Laureate Ivar Giaever
Part I: Methodology
Nuclear Magnetic Resonance Spectroscopy the Chemical Shifts, Coupling Constants and Molecular Geometry
Nuclear Magnetic Resonance Spectroscopy Stereodynamics of Small Molecules
Nuclear Magnetic Resonance Spectroscopy Solution Dynamics of Polymer Chains
Single Crystal Crystallography
Part II: Small Molecules and Ions
The Rotation-Inversion Dichotomy in Trialkylamines Diethyl Methylamine and Triethylamine
Pyramidal Carbanions
Delocalization in Diarylmethyl Anions Probe of Solution Ion States?
Steric Effects on Electron Transfer Reactions of Sulfonamides
The Effect of Isotopic Perturbation on NMR Spectra. A New Method for Distinguishing Rapidly Equilibrating Molecules from Symmetric Molecules
Part III: Medium Size Molecular Systems
Conformational Mobility of the Backbone of Cyclic Tripeptides
Multinuclear NMR Studies of Crown and Cryptand Complexes
Frontier Orbital Models for and Rearrangements of Organotranzition Metal Compounds
Spectroscopic and X-ray Crystallographic Structural Studies of Mo(IV), Mo(V) and Mo(VI) Complexes with Linear Thiolate Ligands
Part IV: Systems of Higher Order. Nucleic Acid Statics and Dynamics
The Diverse Spatial Configurations of DNA and the Evidence for a Vertically Stabilized Double Helix
Does DNA Have Two Structures that Coexist in Equilibrium
Structure, Fluctuations and Interactions of the Double Helix
Internal Twisting of Short DNA Segments
The Flexible DNA Double Helix
Conformational Flexibility of the Polynucleotide Chain
Accessible Surface Areas of Nucleic Acids and their Relation to Folding, Conformational Transition, and Protein Recognition
The Coil Form of Poly(rU): A Model Composed of
Minimum Energy Conformers that Matches Experimental Properties
Modelling of Drug-Nucleic Acid Interactions Intercalation Geometry of Oligonucleotides
DNA Structure and Its Distortion by Drugs
Structure and Dynamics of Poly(dG-dC) in Solution, Steroid Diamine*Nucleic Acid Complexes and Generation of an "Alternating B-DNA" Conformation in High Salt
Spectroscopic Studies of Drug Nucleic Acid Complexes
Part V: Intact Biological Systems
Carbon-13 Cross-Polarization Magic-Angle NMR Studies of Biological Systems
NMR Zeugmatographic Imaging of Organs and Organisms
Index