Imidazole-Based Drug Discovery

Imidazole-Based Drug Discovery covers all categories of imidazole and its derivatives, synthesis, pharmacological applications and drug-based studies. Imidazole scaffolds act as a channel between organic synthesis and medicinal chemistry and compel researchers to explore new drug candidates. This book provides detailed coverage of several greener synthetic protocols and pharmacological applications of imidazole derivatives that are useful to researchers working on designing more promising clinical lead compounds with this scaffold. It also includes information on past decades of research on the synthesis and biological applications of imidazole derivatives.

This is an ideal resource for researchers in organic chemistry both in academic and industrial settings, as well as postgraduates in chemistry and medicinal chemistry.

• Reviews the most current developments and future perspectives of imidazole on different disease therapies to achieve the ultimate goal of disease eradication
• Discusses the role of imidazole in contemporary science, technological innovation, drug development, critical challenges and future research directions
• Covers emerging trends on different eco-benign pathways to synthesize imidazole derivatives for the development of simpler synthetic protocols

Auteur

Dr. Shikha Agarwal has been Assistant Professor in the Department of Chemistry, Mohanlal Sukhadia University, Udaipur since 2012. She received the Gold Medal in MSc Chemistry in 2006 from the University of Rajasthan, Jaipur, and was a recipient of JRF and SRF from CSIR, New Delhi and qualified GATE-2006 in the 98th percentile. She was awarded a PhD from the University of Rajasthan, Jaipur in 2011.
Dr. Agarwal has published more than 50 research articles in various national and international journals, and has published several books and contributed chapters. Her research interests are in synthetic organic chemistry, green chemistry, catalysis, and combinatorial and medicinal chemistry.

Contenu

1. Imidazole and its Derivatives: Introduction and Synthetic Aspects
   
   2. Biological Profile of Imidazole based Compounds as Anti-Cancer Agents
   3. Recent Advancements on Imidazole containing Heterocycles as Anti-Tubercular Agents
   4. Imidazole Derivatives: Impact and Prospects in Anti-Viral Drug Discovery
   5. Imidazole Heterocycles: Therapeutically Potent Lead Compounds as Anti-Microbials
   6. Imidazole containing Heterocycles as Antioxidants
   7. Miscellaneous Biological Activity Profile of Imidazole Based Compounds: An Aspirational Goal for Medicinal Chemistry
   8. Imidazole Based Drugs and Drug Discovery: Present and Future Perspectives