Scientific Advances in Reconstructive Urology and Tissue Engineering

Scientific Advances in Reconstructive Urology and Tissue Engineering is a comprehensive overview of reconstructive urology that spans male and female, pediatric, neuro-urology and trauma. Traditionally, this field has been focused solely on surgical principles with little attention to basic and translational research. However, recent advances in acellular matrices, scaffolds, stem cells and tissue engineering have changed this focus. This publication is the perfect bridge and definitive tome of the advances that will move the translational and basic science of reconstructive urology forward and allow readers to implement the findings in clinical practice.

Through the use of both current case studies and future implications, the content bridges the gap from bench to bedside making it the perfect reference for translational benign urology researchers who wish to move the field of reconstructive surgery forward.

• Includes real-world applications of current research to help readers get rapidly up-to-speed on which research results are appropriate for immediate implementation
• Presents the underlying mechanism of urologic disease processes pertinent to reconstructive urology for comprehensive understanding within the field
• Provides independent guidance to manage specific clinical conditions while also presenting approaches that are applicable to all conditions

Contenu

1. Historic development of translational reconstructive urology and current state of the art 2. Buccal mucosa and its use for urethral reconstruction 3. Use of mesenchymal stem cell-seeded scaffolds for bladder augmentations 4. Pathophysiology of radiation-induced urethral strictures and therapeutic strategies optimizing outcomes of surgical repair 5. Testosterone supplementation to prevent artificial urinary sphincter erosion in hypogonadal men 6. The molecular profile of urethral stricture disease 7. Pathophysiology of Urethral Stricture and optimizing urethroplasty outcomes 8. Engineered solutions for urethral stricture disease: From bench to bedside 9. Novel approaches correcting form and function in sexual medicine 10. Pathophysiology of underactive bladders 11. Tissue engineering in pediatric urology 12. Engineered neovaginas in patients with MRKH syndrome 13. Using cultured autologous oral epithelial cells for vaginoplasty in male-to-female transsexuals 14. Underlying mechanisms of rejection in penile vascularized composite allotransplantation