Receptors

Methods in Neurosciences, Volume 11: Receptors: Model Systems and Specific Receptors is a compilation of papers that describes techniques and information that are important to the neurosciences. This volume discusses preferred receptor techniques, molecular techniques, and methods to determine receptor subclasses and localization in the ligand design.
The first paper discusses the steroid receptor found in the central nervous system for steroid hormones that affects strongly the structure and function of both developed and immature nervous systems. Another paper describes how a glycoprotein of 79.5 kDa (transferrin) carries iron in the blood stream for delivery to different tissues, after the transferrin has bound with a specific receptor on the surface of the cell. This book also explains the binding sites of pituitary adenylate cyclase-activating polypeptide in the human brain, while one paper analyzes the neurotensin receptors during the primary culture of neurons. This volume then also analyzes the structure and function of the fast nerve growth factor receptor, particularly how a signal on the outside of a cell is transmitted to the cell's interior.
This collection is helpful for microbiologists, cellular researchers, students, and professors in the discipline of neurosciences.

Contenu

Contributors to Volume 11
Preface
Volumes in Series

1. Steroid Receptors in the Central Nervous System
2. Membrane Receptor for Glucocorticoids in Mammalian Neurons
3. Interleukin 1 Receptors in the Brain-Endocrine-Immune Axis
4. Vasoactive Peptides and Their Receptors
5. Melanotropin Receptors of the Brain
6. Melatonin Binding Sites
7. Transferrin Receptors in the Central Nervous System
8. Binding Sites of Pituitary Adenylate Cyclase-Activating Polypeptide in Human Brain
9. Role of Cholecystokinin Type B Receptor in Nociception Studied with Peptide Agonists and Antagonists
10. Cholecystokinin Receptors: Radioligand Binding and Afñnity Labeling
11. Endothelin Receptors in Neural Systems
12. Natriuretic Peptide Receptors
13. Structural and Functional Identification of Insulin-like Growth Factor Receptors
14. Methods for Studying Central Serotonergic Receptors
15. Analysis of Serotonin 5-HT1A Receptors in Primary Neuronal Culture
16. Characterization of the Bombesin/Gastrin-Releasing Peptide Receptor in Swiss 3T3 Fibroblasts
17. Receptors for Bombesinlike Peptides in the Rat Central Nervous System
18. Retinal Insulin Receptors
19. Pancreatic Polypeptide Receptors in Rat Brain
20. Neurotensin Receptors in Primary Culture of Neurons
21. Analysis of the Structure and Function of the Fast Nerve Growth Factor Receptor
22. Solubilization and Physicochemical Characterization of 5-HT3 Receptor-Binding Sites
23. Solubihzadon and Characterization of the Receptor for Gastrin-Releasing Peptide
24. Assays for Pituitary Adenylate Cyclase-Acdvadng Peptide Receptors Coupled to Adenylate Cyclase: Comparison between Rat Brain and Human Neuroblastoma Cells
    Index