Receptors as Supramolecular Entities

Advances in the Biosciences, Volume 44: Receptors as Supramolecular Entities exemplifies the concept of transmitter and cotransmitter interactions using GABA receptor as a model. The book contains papers on the interaction of sulpiride and other substituted benzamides with dopamine receptors where the result of receptor stimulation is not a stimulation of cyclic AMP formation. The text also offers a panoramic view of the concepts that are being elaborated to reach a better understanding of the function of the receptors for the most important neurotransmitters operative in brain.

Contenu

Introduction
Dopamine Receptors
Radioligand Binding Studies of Dopamine Receptors in the Central Nervous System
Inhibitory Coupling of Dopamine Receptors to Adenylate Cyclase in Rat Anterior Pituitary
Possible Functional Meaning of the Coexistence of ,Monoamines and Peptides in the Same Neurons: A Study on the Interactions Between Cholecystokinin-8 and Dopamine in the Brain
Behavioral Effects of Prolactin: The Involvement of Brain Dopamine
DA Autoreceptors in the Substantia Nigra: Their Involvement in the Control of Nigral DA Synthesis
Modifications of Dopamine Receptors in Rat Striatum after Chronic Administration of L-Dopa
D2 Receptors Modulating Dopamine Synthesis in Striatal Synaptosomes
Evidence Against the D1 and D2 Dopamine Receptor Hypothesis: Studies with Sulpiride
Sulpiride and Other Benzamides as Specific Antagonists at the D2 Dopamine Receptor
Estrogen Modulation of Dopamine Autoreceptors
Activation of Dopaminergic Neurons by Sulpiride
Functional Similarities Between Benzamides and Other Neuroleptics
Behavioral and Biochemical Effects in the Adult Rat After Prolonged Postnatal Administration of Cataleptogenic and Noncataleptogenic Neuroleptics
Biochemical Pharmacology of Dopamine Neurons Innervating the Neurointermediate Lobe of Pituitary Gland
Substituted Benzamide Drugs as Selective Agents for Distinguishing Cerebral Dopamine Receptor Subtypes
The Supramolecular Organization of Receptors for Gamma-Aminobutyric Acid (GABA)
Neurochemical Indices of GABA Utilization in the Nigrostriatal System
Role of GABAergic Mechanisms within Cerebellar Nucleus Fastigii in the Control of Posture and in the Mechanism of Action of Benzodiazepines
Age Induced Loss of the Functional Link Between Benzodiazepine and GABA Binding Sites in the Rat Retina
Effects of Inhibitors of GABA Metabolism and Transport on GABA Output from the Cerebral Cortex
Distribution and Circadian Variations of GABA in Hypothalamic Areas Regulating Food Intake
An Electroencephalographic Analysis of the Convulsant Benzodiazepine 1,3-Dihydro-5-Methyl-2H-1,4-Benzodiazepine-2-0ne (RO 5 3663)
3H-Diazepam Binding and Interaction Between GABA and Benzodiazepine Binding Sites in Different Brain Regions of Aged Rats
Opiate Receptors and their Ligands
Evidence that Serotonin Modulates Opiate Neuronal Activity in Striatum
Bestatin: A Selective and Potent Inhibitor of Enkephalin Aminopeptidase
Effect of Two Modified Met-Enkephalins on the EEG and Behavior of Rats and Rabbits
Acute Tolerance to and Dependence upon Opioid Peptides in Single Spinal, Striatal and Cortical Neurons of Rats
A Potent Aphrodisiac Drug Combination; Naloxone and N-n-Propyl Norapomorphine
Histamine Receptors and Actions in Mammalian Brain
Effect of Adenosine and ATP on Acetylcholine Release from Brain Slices
Noradrenaline Receptor Subtypes: Their Role in the Modulation of the Release of the Neurotransmitter
Failure of Prolactin to Inhibit Sexual Behavior in the Male Rat
Antidepressants: Effects on Adrenal Activity and Brain Glucocorticoid Binding
Physiological and Pharmacological Modulation of Hypothalamic Prolactin Receptors
Interaction Between ACTH and Beta-Endorphin at the CNS Level