Protides of the Biological Fluids

Protides of the Biological Fluids contains the proceedings of the 26th Colloquium in 1978. Two topics are highlighted, the first one being the immune complexes and the second one being the cytoskeletal proteins.
This book is organized into three sections, namely, Immune Complexes, Cytoskeletal Proteins, and Techniques. The Immune Complexes section states the biochemical problems and answers some intriguing clinical problems in this field. This section details the theory of the antigen/antibody reaction, the isolation of complexes, and the nature of the antigen. The Cytoskeletal Proteins section discusses the theoretical aspect of cell structure. The last section describes the assay methods and individual protein assays.

Contenu

Contents
Preface
Acknowledgments
The Seventh Arne Tiselius Memorial Lecture
Are Circulating Immune Complexes The Key To Immunopathology?
Section A. Immune Complexes
A.1. Detection Methods and Reagents
Pitfalls in the Use of Biologic Reagents For the Detection of Immune Complexes
Preparation of Stabilized Human IgG Aggregates of Known Size and Their Reactivity in Immune Complex Assays
Automated Determination of Circulating Immune Complexes by Pacia
A Semi-Automated System Permitting Analysis of Immune Complex Components
A New Solid Phase Assay System For Immune Complexes Using Fc-Fragments of Human IgG (Spaif)
The Use of Bovine Conglutinin As A Reagent For Detecting Immune Complexes
Detection of Circulating Immune Complexes by Radioimmunoassay with Monoclonal Rheumatoid Factor: Comparison with Clq Binding and Raji Cell Radioassays in Cancer
Rheumatoid Factor Radioimmunoassay For Immune Complexes
Detection of Immune Complexes in Human Renal Transplantation by Using Anti-Antibody
Measurements of Immune Complex Formation by Difference Turbidity
A Titration Method For Rf and Immune Complexes
A.2. Theory of Antigen-Antibody Reaction
Antibody Structures and Effector Functions: Immunoglobulin Carbohydrates Revisited
The Alternative Pathway of Complement Activation: Initiation, Amplification and Control
Functional Differentiation of Immunoglobulin G
The Precipitin Reaction: The Importance of The Fc-Portion of IgG
Calculation of Immune Complex Distributions
Computer Modeling of Precipitin Reactions
Modification of The Interaction Between Platelets and Immune Complexes by Cl Subcomponents (First Component of Complement)
Light Scattering by Growing Antigen-Antibody Complexes
A.3. Isolation of Immune Complexes
Immunologie Properties of Aggregated Human IgG: Column Fractionation of Thermal Aggregates
Comparison of Raji Cells and Protein A-Sepharose For Isolation of Soluble Immune Complexes From Serum
Isolation of Soluble Immune Complexes by Affinity Chromatography Using Staphylococcal Protein-A Sepharose As Substrate
Purification of Soluble Immune Complexes From Serum Using Solid-Phase Conglutinin and Clq
A.4. Nature of Antigen in Immune Complexes
Are Immune Complexes Immunoglobulin Aggregates?
A Multi-Faceted Approach To Characterization and Isolation of Immune Complexes
Milk Precipitins and Circulating Immune Complexes in Selective IgG Deficiency
Soluble Immune Complexes in Subjects with Selective Iga Deficiency
Immunoglobulin-Alkaline Phosphatase Complexes in Human Serum
A.5. Fate of Immune Complexes
Transport of Immune Complexes To Germinal Centers
Structural Determinants For the Circulating Life-Times of Immunoglobulins and Immune Complexes
Clearance of Soluble Immune Complexes and Aggregates
A.6. Immune Complexes in Arthritis
Analysis of Immune Complexes in Rheumatoid Arthritis
Circulating Immune Complexes in Ankylosing Spondylitis
Clq Reactive Immune Complexes in Sjogren's Syndrome
Immune Complexes in Rheumatoid Arthritis : Correlations with Clinical Features and Effects of Gold
Thrombocyte Aggregation by Sera and Antiglobulin Complexes From Patients with Rheumatoid Arthritis
A.7. Immune Complexes in Viral, Bacterial, Parasitic Infections
A.7.1. Viral Infections
A.7.2. Bacterial Infections
A.7.3. Parasitic Infections
A.8. Immune Complexes in Systemic Lupus (SLE)
Activity of Systemic Lupus Erythematosus (SLE) Followed by Circulating Immune Complexes
The Heterogeneity of Immune Complexes in Disease
The Occurrence and Significance of Circulating Anti-ds-DNA And Free DNA in SLE
Detection of Immune Complexes in Connective Tissue Diseases: A Comparison of Three Radioassays
The Occurrence of Immune Complexes in Patients with Multiple Sclerosis
A.9. Immune Complexes in Nephritis
Immune Complexes in Human Glomerulonephritis. A Study of 99 Cases Using A Clq Binding Assay
Clearance and Glomerular Deposition of Circulating Immune Complexes
Protein Transport in Glomeruli with Immune Complexes
Clearance and Glomerular Localization of Well Defined Immune ComplexesEs
Circulating Immune Complexes in Acute Rheumatic Fever and Acute Poststreptococcal Glomerulonephritis
Role of HBsAg Immune Complexes in Glomerulonephritis of Essential Mixed Cryoglobulinemia (EMC)
Detection of Circulating Immune Complexes with Clq Binding Test in Glomerulonephritis and Complement Profiles
Immune Complex Binding To Human Glomerular Complement Receptors
Clq Binding Activity of Sera From Renal Transplanted Patients Treated with Anti-Lymphocyte Globulins
Clq Binding Immune Complexes and C3 Nephritic Factor (C3nef) in Hypocomplementemic Human Glomerulonephritis
Occurrence of Iga in Tissues of Patients with Alcoholic Hepatic Disease, Anaphylactoid Purpura and Recurrent - Often Benign - Hematuria
Application of Solid Phase Clq Assay in Sera From Nephropathic Patients
Immune Complex Type Glomerulonephritis in Rabbit Induced by A Streptococcal Antigen
Circulating Immune Complexes in Renal Transplant Recipients
A. 10. Immune Complexes in Cancer
Relevance of Circulating Immune Complexes in Cancer Sera
Evaluation of Prognosis and Tumor Extent in Cancer Patients by Detecting Circulating Immune Complexes with The 125i-Clq-Binding Assay
Serial Testing For Immune Complexes in Malignant Melanoma
Detection, Isolation and Characterization of Immune Complexes in Malignant Melanoma
Demonstration of Circulating Immune Complexes in Melanoma Patients by Means of A Granulocyte Fagocytosis Test
Clinical Implications of Elevated Levels of Circulating Immune Complexes in Patients with Malignant Melanoma
Circulating Immune Complexes in Nasopharyngeal Carcinoma Patients and Their Household Contacts
Circulating Immune Complexes in Sera of Patients with Lung Cancer
Studies On Identification of Antigens in Immune Complexes of Lung Cancer Patients
Circulating Immune Complexes in Multiple Myeloma
A.II. Clinical Screening For Immune Complexes
Detection of Circulating Immune Complexes by The Ciq Binding Activity CLQBA) in Liver Diseases with Or Without HBsAg
The Clq Deviation Test For the Detection of Circulating Immune Complexes, A 2-Year? Survey in A University Medical Center
Clinical Value of Immune Complex Assays
Methods of De-Complementation and The Detection of IC
Cryoglobulins As Immune Complexes: An Immunochemical Study of Cryoprecipitates
Thyroglobulin and Anti-Thyroglobulin Immune Complexes in Human Sera
Serial Measurement of Circulating Immune Complexes in Leukemia
A. 12. Therapy of Immune Complex Syndromes
Intensive Plasmapheresis in Idiopathic Thrombocytopenic Purpura
Monitoring of Plasmapheresis in Sle by Immune Complex Assays
Plasmapheresis in the Management of Systemic Lupus Erythematosus: The Relevance of Tests For Circulating Immune Complexes
The Effect of Plasmapheresis On Circulating Immune Complexes Measured by Raji-Cell and Indire…