Precision Molecular Pathology of Hodgkin Lymphoma

This text provides a comprehensive and up-to-date overview of Hodgkin lymphoma. The volume reviews every facet of the cancer in great detail, including pathology, pathobiology, molecular genetics, microenvironment, epidemiology, treatment, and new therapeutic advances. The specific role of the lymphoma microenvironment is addressed, and the relationship of Hodgkin lymphoma to related non-Hodgkin lymphomas is covered as well. Written by experts in the field, Precision Molecular Pathology of Hodgkin Lymphoma is a valuable resource for oncologists, surgeons, pathologists, clinical trainees, and investigators engaged in the diagnosis, treatment, and research studies of this lymphoid neoplasm.

Auteur
S. David Hudnall, MDProfessor of Pathology and Laboratory Medicine
Director, Hematopathology ProgramAssociate Medical Director, Precipio Diagnostics, LLCYale University School of Medicine310 Cedar StreetNew Haven, CT 06520USA
Dr. Ralf KüppersUniversity of Duisburg-EssenDepartment of Molecular GeneticsInstitute of Cell BiologyHufelandstr. 5545122 EssenGermany

Contenu
Introduction.- Clinical features.- Histopathology of Hodgkin lymphoma and closely related lymphomas.- Pathogenesis and molecular genetics of classical Hodgkin lymphoma.- The microenvironment in classical Hodgkin lymphoma.- Role of EBV in classical Hodgkin lymphoma.- Pathobiology of nodular lymphocyte predominant Hodgkin lymphoma.- Composite lymphomas and the relationship of Hodgkin lymphoma to Non-Hodgkin lymphomas.- Epidemiology and genetic risk factors.- Treatment and Prognosis.- Development of targeted therapies.