The Pombe Cdc15 Homology Proteins

Cell migration is an extremely complex but also a carefully orchestrated process. It involves the constant reconstruction of the cell shape, in order to adapt to an ever-changing plethora of external and internal stimuli. Time lapse movies of migrating cells often demonstrate a vigorous ruffling activity of the plasma membrane at the cell periphery

Auteur

Pontus Aspenström is a Group Leader at the Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden. The research activities in his laboratory are focused on signal transduction pathways that regulate cytoskeletal dynamics. His research interests include F-BAR proteins, atypical Rho GTPases and the mammalian Verprolins (WIP, W IRE and CR16). Pontus Aspenström received his PhD from the Uppsala University, Sweden and did a post-doc at MRC-LMCB, University College London, London, UK. He has also served as a Group Leader at the Ludwig Institute for Cancer Research, Uppsala, Sweden.