Polyphenols, Wine and Health

In this book, the effect of nutritional habits and wine consumption on ageing and the main degenerative diseases (cardiovascular, cancer, Alzheimer's, etc.) are considered through the most relevant epidemiological and pharmacological studies. Newly isolated wine polyphenols and tannins are presented and their structures and in vitro biological properties are discussed that could strongly support the hypotheses that those molecules could insure beneficial health effects. This book will be of particular interest to people involved in problems of public health, but also in the wine industry or in wine making, as well as to physicians who are concerned by the difficult question of ageing and its related chronic diseases.

Contenu

Preface. Natural polyphenols as drugs and medicines: potential modes of action; E. Haslam. Polyphenols and Health: Gastrointestinal effects of complex polyphenols from red wine and tea in experimental animal models; P. Dolara. Resveratrol, a novel inhibitor of cyclooxygenase-2 gene expression; A. Dannenberg. Trans-resveratrol and the liver: deactivation of liver myofibroblasts and inhibition of tumor cell invasion; J. Rosenbaum. Polyphenolsfrom from grapes to wine: Understanding the colour of red wines: from anthocyanins to complex pigments; J.C. Rivas-Gonzalo. Physiological Properties of Resveratrol Isomers in Wine: Compositional Changes during Processing; R.-M. Lamuela-Raventos. Wine and Health: The French or the Mediterranean Paradox? Biological mechanisms potentially involved in a protective effect of wine phenols against clinical manifestations of atherothrombosis; L. Drouet. Alcohol and cardiovascular diseases: Epidemiological studies; J. Ferrieres. Polyphenols and cancer prevention; V.E. Steele. Subject Index.