The new Fourth Edition of Bacterial Infections of Humans reflects a decade of important discoveries, technological progress, and valuable new therapies as well as emerging and reemerging infections, resistant strains of bacteria, and threats of bioterrorism. It offers accessible, up-to-date information across the range of disease entities.

As in previous editions, introductory chapters review general concepts of infection and epidemiology, and the chapters devoted to specific infections follow a consistent and highly useful format: historical background, methodology (diagnosis and pathology), biology, descriptive epidemiology, mechanism and routes of transmission, pathogenesis, host responses, methods of prevention and control, and areas for futureresearch. All material has been thoroughly updated, and two chapters on molecular epidemiology and health care-acquired bacterial infections, are entirely new.

A sampling of the 40 diseases and clinical syndromes covered in the Fourth Edition:

Anthrax
Bacterial foodborne disease
Chlamydia
E. coli
Legionellosis
Meningitis
Q fever
Tuberculosis

Bacterial Infections of Humans has been noted for ably complementing textbooks on the subject, and this most current edition remains a major reference for professionals in the field, including public health practitioners, microbiologists, immunologists, researchers studying pathogenic bacteria, clinicians working with infectious disease, and medical or nursing students.

Résumé
In Memoriam of Alfred S. Evans The third edition of Bacterial Infections of Humans is dedicated to Alfred Spring Evans, who died on January 21, 1996, 2 ½ years after a diagnosis of cancer. Al was the senior editor of this textbook, which he founded with Harry Feldman in 1982. Al was a clinician, epidemiologist, educator, ca- lyst for biomedical research, historian, author, speaker, seeker of the truth, sincere friend of students, sports enthusiast, traveler, and truly a man of all seasons. He was a devoted husband to Brigette Klug Evans, father of three children, and grandfather of four. Al was born in Buffalo, New York, on August 21, 1917, to Ellen Spring and John H. Evans, M. D. , one of the United States's ?rst anesthesiologists and an early researcher in the ?eld of oxygen therapy. He received his undergraduate training at the University of Michigan; was awarded an M. D. degree in 1943 from the University of Buffalo; interned in Pittsburgh, Pe- sylvania; and performed his medical residency at the Goldwater Hospital in New York City. He was in the United States Army from 1944 to 1946, assigned as a public health of?cer to a base in Okinawa, Japan. It was there that he met Drs. Albert Sabin and John R. Paul, who came to Okinawa to test a new Japanese encepha- tis vaccine. Al was invited by Dr. Paul to come to Yale Alfred S.

Contenu
Epidemiological Concepts.- Public Health Surveillance.- Molecular Epidemiology.- The Epidemiology of Bacterial Resistance to Antimicrobial Agents.- Anthrax.- Bacterial Foodborne Disease.- Botulism.- Brucellosis.- Campylobacter Infections.- Chancroid.- Chlamydial Infections.- Cholera.- Clostridium difficile.- Diphtheria.- Escherichia coli Diarrhea.- Gonococcal Infections.- Haemophilus influenzae.- Helicobacter pylori.- Legionellosis.- Leprosy.- Leptospirosis.- Listeria monocytogenes Infections.- Lyme Disease.- Meningococcal Infections.- Mycoplasma pneumoniae and Other Human Mycoplasmas.- Healthcare-Acquired Bacterial Infections.- Pertussis.- Plague.- Pneumococcal Infections.- Q fever.- Rocky Mountain Spotted Fever.- Salmonellosis: Nontyphoidal.- Shigellosis.- Evans' Infections of Humans: Staphylococcal Infections.- Streptococcal Infections.- Syphilis.- Syphilis.- Tetanus.- Toxic Shock Syndrome (Staphylococcal).- Tuberculosis.- Nontuberculous Mycobacterial Infections.- Tularemia.- Typhoid Fever.- Yersinia enterocolitica Infections.