Paclitaxel

Paclitaxel: Sources, Chemistry, Anticancer Actions, and Current Biotechnology provides a comprehensive survey of Paclitaxel and its derivatives chemistry, biosynthesis and anticancer activities. In addition, biotechnological methods, including cell cultures, the use of bioreactors and metabolic engineering strategies to improve Paclitaxel production are also discussed. The book discusses topics such as mechanisms of action against cancer, novel forms of Paclitaxel for an effective cancer treatment, strategies for enhancing its bioavailability, and the application of nanocarriers for its delivery and chemotherapy of cancer.

This is a valuable resource for cancer researchers, biotechnologists and members of biomedical field who are interested in the promising anticancer qualities of this antineoplastic drug and how to enhance them for better treatments.

• Presents detailed information about Paclitaxel research, from its discovery to clinical uses and biotechnological routes of commercial production
• Focuses on Paclitaxel development as an effective chemotherapeutic drug, along with its application in different types of cancers
• Encompasses descriptive illustrations and workflows to help the reader fully understand the content and easily apply it to their research

Contenu

1. About Cancers and treatment options- An update
   
   2. Paclitaxel: Chemistry, synthetic analogues and their anticancer properties
   3. Taxol: Mechanisms of action against cancer, an update with current research
   4. Novel forms of Paclitaxel for an effective cancer cure
   5. Clinical pharmacology of Paclitaxel
   6. Strategies for enhancing bioavailability of Paclitaxel for cancer treatment
   7. Application of nanocarriers for Paclitaxel delivery and chemotherapy of cancer
   8. Paclitaxel: Cancer chemotherapy evidences, advantages, and future directions
   9. Anticancer Drug Paclitaxel producing plants. Their taxonomy, morphology, identification, distribution and other botanical details (it also includes color photographs of plants)
   10. Propagation and Micropropagation of Paclitaxel producing plants
   11. Biotechnology of Paclitaxel producing plants (Paclitaxel production through hairy root cultures, suspension cultures, callus cultures etc)
   12. Endophytes for the production of anticancer drug, Paclitaxel
   13. Metabolic engineering strategies to enhance the production of anticancer drug, Paclitaxel
   14. Paclitaxel and Chemoresistance Chapter
   15. Overcoming Paclitaxel Resistance
   16. Paclitaxel and Lung Cancer Treatment
   17. An update on paclitaxel treatment in Breast cancer-pros and cons