New Avenues to Efficient Chemical Synthesis

In modern drug discovery and development, chemical synthesis is one of the key technologies. For the rapid preparation of new test compounds and drug development candidates, several innovative technologies with great potential have emerged. This book offers a compact overview of the current status of these technologies and includes many real-life examples from industry and academic institutions.

Contenu
Microreactors as Tools in the Hands of Synthetic Chemists.- Micro-Fluidic and Lab-on-a-Chip Technology.- Microreactors as New Tools for Drug Discovery and Development.- Microchemical Systems for Discovery and Development.- Isoindolones and Related N-Heterocycles Isoindolones and Related N-Heterocycles via Palladium Nanoparticle-Catalyzed 3-Component Cascade Reactions.- Applying Homogeneous Catalysis for the Synthesis of Pharmaceuticals.- An Integrated Approach to Developing Chemoenzymatic Processes at the Industrial Scale.- Scale-Up in Microwave-Accelerated Organic Synthesis.- Solid Supported Reagents in Multi-Step Flow Synthesis.- Solid-Phase Supported Synthesis: A Possibility for Rapid Scale-Up of Chemical Reactions.- Microstructured Reactors for Development and Production in Pharmaceutical and Fine Chemistry.