Organozinc Derivatives and Transition Metal Catalysts

Organozinc reagents are less reactive than Grignard reagents but they?are much more chemoselective. Since the?Negishi cross-coupling reaction developed by Ei-ichi Negishi, who was awarded the Nobel Price in chemistry in 2010, a number of cross-coupling reactions involving organozinc derivatives and transition metal catalysts (Pd, Ni, Fe, Co, Cu, ...) has been tuned up to form C-C bonds. This book on 'Organozinc derivatives and transition metal catalysts' has been?written by experts in the field and is a complement to the book entitled 'Grignard reagents and transition metal catalysts' (a De Gruyter book, edited by J. Cossy).

Grignard reagents or organozinc reagents, that is the question? From a given substrate, what is the best organometallic?reagent and the best transition metal to form a C-C bond by using a cross-coupling reaction? The solution might be found in these two books.

Janine Cossy, ESPCI ParisTech, Paris, France.