Neurosecretion: Secretory Mechanisms

How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from both vertebrate and invertebrate systems. The contributions span in vivo and in vitro studies that address: state-dependent plasticity, relevance of firing patterns, membrane properties, calcium flux (including dynamic imaging and homeostasis), and molecular mechanisms of exocytosis, including from non-neuronal secretory cells. The chapters focus not only on research results but also on how experiments are conducted using state-of-the-art techniques, and how the resulting data are interpreted.

While there are many books on the secretory properties of neurons, this is the first to focus on the distinctive secretory properties of neuroendocrine neurons. Accordingly, it offers an important text for undergraduate and graduate neuroscience students, and will also appeal to established scientists and postdoctoral fellows.

This is the eighth volume in the Masterclass in Neuroendocrinology series* - now a co-publication between Springer Nature and the INF (International Neuroendocrine Federation).

*Volumes 1-7 published by Wiley

Contenu

Chapter 1: Neurosecretion: An overview - Harold Geiner

Chapter 2: Neurosecretion: hypothalamic somata vs. neurohypophysial terminals - Govindan Dayanithi and José R. Lemos Chapter 3: Cycle ADP-ribose and heat reagulate oxytocin release via CD38 and TRPM2 in the hypothalamus - Haruhiro Higashida and Olga Lopatina

Chapter 4: Somato-Dendritic secretion of neuropeptides - Colin Brown, Mike Ludwig and Javier E. Stern

Chapter 5: Neurosecretory vesicles: structure, distribution, release and breakdown - John F. Morris

Chapter 6: Molecular controls on regulated neurotransmitter and neurohormone secretion - Victor Cazares and Edward Stuenkel

Chapter 7: Secretory Astrocytes- Alexei Verkhratsky and Robert Zorec

Chapter 8: Action Potential-Induced Ca2+ Influx for Both Acute and Sustained Insulin Secretion in Pancreatic Beta Cells - Haiqiang Dou and Zhuan Zhou

Chapter 9: Plasticity in the morphology of lactotrophs and folliculo-stellate cells and prolactin secretion- Helen C Christian Chapter 10: Neuroendocrine and metabolic regulation of plasma growth hormone secretory profiles- Lili Huang, Yang Chen, Zhengxiang Huang and Chen Chen

Chapter 11: Role of the TWIK-related potassium (TREK)-1 channels in the regulation of adrenocorticotrophin (ACTH) secretion from pituitary cortitropes- Amy Tse, Any K. Lee and Frederick W. Tse

Chapter 12: How do Bacterial Neurotoxins Affect Neurosecretion- Bernard Poulain and Frédéroc Doussau

Chapter 13: Secretory mechanisms in Paramecium- Helmut Plattner