Neurological Complications of Systemic Cancer and Antineoplastic Therapy

Neurological Complications of Systematic Cancer and Antineoplastic Therapy, Second Edition provides an expanded, updated and in-depth review of common manifestations related to neurology that occur in patients with systemic cancer. These include brain metastases, spinal cord compression, cerebrovascular events, and leptomeningeal disease. The book also discusses neurological complications related to treatments such as radiation and chemotherapy and is an essential reference for the practicing neurologist and oncologist.

Sections in this new release cover the pathophysiology and molecular biology of cancer and the metastatic phenotype, Metastatic spread to cranial and peripheral nerves and brachial and lumbosacral plexuses, Metabolic and nutritional disorders, CNS infections, Neurological complications of immunotherapy and bone marrow transplants, Neurological complications of new molecular agents and immuno-modulatory drugs, and more.

• Summarizes the neurologic effects of both cancer and cancer treatment
• Provides scientific and clinical information relevant to research and treatment
• Identifies neurological complications by tumor type and tumor therapy
• Covers GI, lung, breast, gynecological, head and neck cancers, and more
• Includes radiotherapy, chemotherapy, immunotherapy, and new drugs
• Contains melanoma, lymphoma, sarcoma, myeloma, leukemia, and more

Contenu

SECTION I. Metastatic Neurological Complications 1. Common symptoms at presentation of nervous system metastases 2. Neuroimaging of systemic metastatic disease 3. Nonimaging evaluation of patients with nervous system metastases 4. Biology and pathophysiology of central nervous system metastases 5. Intracranial metastases 6. Neurosurgical approaches to the treatment of intracranial metastases 7. Epidural metastasis and spinal cord compression 8. Leptomeningeal metastasis 9. Cranial nerve involvement by metastatic cancer 10. Cancer-related plexopathies

SECTION II. Nonmetastatic Neurological Complications 11. Cerebrovascular complications of malignancy 12. Metabolic and nutritional nervous system dysfunction in cancer patients 13. Central nervous system infections in cancer patients 14. Diagnosis and treatment of paraneoplastic neurological disorders

SECTION III. Neurological Complications of Specific Neoplasms 15. Neurological complications of lung cancer 16. Neurological complications of breast cancer 17. Neurological complications of melanoma 18. Neurological complications of lymphoma 19. Neurological complications of the leukemias 20. Neurological complications of systemic cancer of the head and neck 21. Neurological complications of gynecological cancers 22. Neurological complications of GI cancers 23. Neurologic complications associated with genitourinary cancer 24. Sarcoma and the nervous system 25. Neurological complications of multiple myeloma 26. Neurologic complications in the treatment of childhood malignancies

SECTION IV. Neurological Complications of Antineoplastic Therapy 27. Neurological complications of radiation therapy 28. Neurological complications of systemic cancer and antineoplastic therapy 29. Neurological complications of hematopoietic stem cell transplantation 30. Chemotherapy-induced peripheral neuropathy 31. Neurological complications of immunotherapy and monoclonal antibody therapy 32. Neurological complications of immune modulatory therapy 33. Neurological complications of steroids and of supportive care

SECTION V. Psychiatric, Pain, Psychosocial, and Supportive Care Issues 34. Psychiatric aspects of care in the cancer patient 35. Chronic cancer pain syndromes and their treatment 36. Psychosocial issues in cancer patients with neurological complications 37. Supportive care