Nanoscience and Nanotechnology for Human Health

Unique in combining the expertise of practitioners from university hospitals and that of academic researchers, this timely monograph presents selected topics catering specifically to the needs and interests of natural scientists and engineers as well as physicians who are concerned with developing nanotechnology-based treatments to improve human health. To this end, the book cover the materials aspects of nanomedicine, such as the hierarchical structure of biological materials, the imaging of hard and soft tissues and, in particular, concrete examples of nanotechnology-based approaches in modern medical treatments. The whole is rounded off by a discussion of the opportunities and risks of using nanotechnology and nanomaterials in medicine, backed by case studies taken from real life.

Auteur
Bert Muller is Professor for Materials Science in Medicine at the University of Basel and teaches physics at ETH Zurich. He received a diploma in mechanical engineering, followed by M.Sc. degrees in Physics and English from the Dresden University of Technology, and obtained a PhD in experimental physics from the University of Hannover, Germany. For his achievements he was granted with the Morton M. Traum Award of the American Vacuum Society. Afterwards, he worked as researcher at the Paderborn University, Germany, as Feodor Lynen Fellow and research associate at the EPF Lausanne and as team leader at ETH Zurich. He has become a faculty member of the Physics Department at ETH Zurich. Ten years ago he has founded the Biomaterials Science Center. Currently, this center has more than twenty researchers dealing with nanotechnology-based artificial muscles for incontinence treatment, smart nano-containers to treat cardiovascular diseases, high-resolution X-ray imaging to visualize the human body down to the molecular level, computational sciences of tissues in health and disease and other applications of physics and nanosciences in medicine and dentistry. He is Fellow of SPIE and an active member of the European Academy of Sciences and Arts.

Marcel Van de Voorde has 40 years` experience in European Research Organisations including CERN-Geneva, European Commission, with 10 years at the Max Planck Institute in Stuttgart, Germany. For many years, he was involved in research and research strategies, policy and management, especially in European research institutions. He holds a Professorship at the University of Technology in Delft, the Netherlands, as well as multiple visiting professorships in Europe and worldwide. He holds a doctor honoris causa and various honorary Professorships.
He is senator of the European Academy for Sciences and Arts, in Salzburg and Fellow of the World Academy for Sciences. He is a Fellow of various scientific societies and has been decorated by the Belgian King. He has authored of multiple scientific and technical publications and co-edited multiple books in the field of nanoscience and nanotechnology.

Contenu

Nanomedicine: Present Accomplishments and Far-Reaching Promises

PART I. INTRODUCTION TO NANOSCIENCE IN MEDICINE OF THE TWENTY-FIRST CENTURY
Challenges and Opportunities of Nanotechnology for Human Health
Nanoscience and Nanotechnology and the Armory for the Twenty-First Century Health Care
Nanomedicine Activities in the United States and Worldwide

PART II. LEADING CAUSE OF DEATH: CARDIOVASCULAR DISEASES
Challenges in Cardiovascular Treatments Using Nanotechnology-Based Approaches
Smart Container for Targeted Drug Delivery
Human Nano-Vesicles in Physiology and Pathology
Challenges and Risks of Nanotechnology in Medicine: An Immunologist's Point of View

PART III. SECOND MOST COMMON CAUSE OF DEATH: CANCER
Challenges of Applying Targeted Nanostructures with Multifunctional Properties in Cancer Treatments
Highly Conformal Radiotherapy Using Protons
Self-Organization on a Chip: From Nanoscale Actin Assemblies to Tumor Spheroids
The Nanomechanical Signature of Tissues in Health and Disease

PART IV. MOST COMMON DISEASES: CARIES, MUSCUSKELETAL DISEASES, INCONTINENCE, ALLERGIES
Revealing the Nano-Architecture of Human Hard and Soft Tissues by Spatially Resolved Hard X-Ray Scattering
Regenerative Dentistry Using Stem Cells and Nanotechnology
Nanostructured Polymers for Medical Applications
Nanotechnology in the Treatment of Incontinence
Nanomedicine in Dermatology: Nanotechnology in Prevention, Diagnosis, and Therapy

PART V. BENEFITTING PATIENTS
Therapeutic Development and the Evolultion of Precision Medicine
Benefits from Nanoscience and Nanotechnology: Benefitting Patients

Index