Organic Synthesis and Molecular Engineering

The theory, methods, and practices needed to build molecules
and supramolecular systems

Using a synthetic approach to organic materials chemistry, this
book sets forth tested and proven methods and practices that make
it possible to engineer organic molecules offering special
properties and functions. Throughout the book, plenty of real-world
examples demonstrate the countless possibilities of creating
one-of-a-kind molecules and supramolecular systems to support a
broad range of applications. The book explores applications in both
materials and bioorganic chemistry, including molecular
electronics, energy storage, sensors, nanomedicine, and enzyme
engineering.

Organic Synthesis and Molecular Engineering consists of
fourteen chapters, each one contributed by one or more leading
international experts in the field. The contributions are based on
a thorough review and analysis of the current literature as well as
the authors' firsthand experience in the lab engineering new
organic molecules. Designed as a practical lab reference, the book
offers:

• Tested and proven synthetic approaches to organic materials
  chemistry

• Methods and practices to successfully engineer functionality
  into organic molecules

• Explanations of the principles and concepts underlying
  self-assembly and supramolecular chemistry

• Guidance in selecting appropriate structural units used in the
  design and synthesis of functional molecules and materials

• Coverage of the full range of applications in materials and
  bioorganic chemistry

• A full chapter on graphene, a new topic generating intense
  research

Organic Synthesis and Molecular Engineering begins with
core concepts, molecular building blocks, and synthetic tools.
Next, it explores molecular electronics, supramolecular chemistry
and self-assembly, graphene, and photoresponsive materials
engineering. In short, it offers everything researchers need to
fully grasp the underlying theory and then build new molecules and
supramolecular systems.

Auteur

MOGENS BRØNDSTED NIELSEN, PhD, is Professor of
Organic Chemistry at the University of Copenhagen, where he teaches
courses in advanced organic chemistry, heterocyclic chemistry, and
supramolecular chemistry. Dr. Nielsen has published more than 100
peer-reviewed papers, monographs, and book chapters.

Résumé

The theory, methods, and practices needed to build molecules and supramolecular systems

Using a synthetic approach to organic materials chemistry, this book sets forth tested and proven methods and practices that make it possible to engineer organic molecules offering special properties and functions. Throughout the book, plenty of real-world examples demonstrate the countless possibilities of creating one-of-a-kind molecules and supramolecular systems to support a broad range of applications. The book explores applications in both materials and bioorganic chemistry, including molecular electronics, energy storage, sensors, nanomedicine, and enzyme engineering.

Organic Synthesis and Molecular Engineering consists of fourteen chapters, each one contributed by one or more leading international experts in the field. The contributions are based on a thorough review and analysis of the current literature as well as the authors' firsthand experience in the lab engineering new organic molecules. Designed as a practical lab reference, the book offers:

• Tested and proven synthetic approaches to organic materials chemistry
• Methods and practices to successfully engineer functionality into organic molecules
• Explanations of the principles and concepts underlying self-assembly and supramolecular chemistry
• Guidance in selecting appropriate structural units used in the design and synthesis of functional molecules and materials
• Coverage of the full range of applications in materials and bioorganic chemistry
• A full chapter on graphene, a new topic generating intense research
  Organic Synthesis and Molecular Engineering begins with core concepts, molecular building blocks, and synthetic tools. Next, it explores molecular electronics, supramolecular chemistry and self-assembly, graphene, and photoresponsive materials engineering. In short, it offers everything researchers need to fully grasp the underlying theory and then build new molecules and supramolecular systems.

Contenu

Acknowledgements vii

Contributors ix

1 Introduction 1

Mogens Brøndsted Nielsen

2 Organic Building Blocks for Molecular Engineering 4

Kasper Lincke and Mogens Brøndsted Nielsen

3 Design and Synthesis of Organic Molecules for Molecular
Electronics 46

Karsten Jennum and Mogens Brøndsted Nielsen

4 Carbon Nanotubes and Graphene 76

Helena Grennberg

5 H-Bond Based Nanostructuration of Supramolecular Organic
Materials 128

Tomas Marangoni and Davide Bonifazi

6 Molecular Systems for Solar Thermal Energy Storage and
Conversion 179

Kasper Moth-Poulsen

7 Strategies to Switch Fluorescence with Photochromic Oxazines
197

Erhan Deniz, Janet Cusido, Massimiliano Tomasulo, Mutlu Battal,
Ibrahim Yildiz, Marco Petriella, Mariano L. Bossi, Salvatore
Sortino, and Françisco M. Raymo

8 Supramolecular Redox Transduction: Macrocyclic Receptors for
Organic Guests 213

Sébastien Goeb, David Canevet, and Marc Sallé

9 Detection of Nitroaromatic Explosives Using
TTF-Calix[4]pyrroles 257

Karina R. Larsen, Kent A. Nielsen, Jonathan L. Sessler, and Jan
O. Jeppesen

10 Recognition of Carbohydrates 284

Martina Cacciarini

11 Cyclodextrin Based Artificial Enzymes: Synthesis and Function
305

Christian Marcus Pedersen and Mikael Bols

12 Organozymes: Molecular Engineering and Combinatorial
Selection of Peptidic Organo and Transition Metal Catalysts
333

Morten Meldal

13 Dendrimers in Biology and Nanomedicine 361

Jørn Bolstad Christensen

14 Dynamic Combinatorial Chemistry 393

Brian Rasmussen, Anne Sørensen, Sophie R. Beeren, and
Michael Pittelkow

Index 437