Microfluidics and BioMEMS Applications

Microfluidics and BioMEMS Applications central idea is on microfluidics, a relatively new research field which finds its niche in biomedical devices, especially on lab-on-a-chip and related products. Being the essential component in providing driving fluidic flows, an example of micropump is chosen to illustrate a complete cycle in development of microfluidic devices which include literature review, designing and modelling, fabrication and testing. A few articles are included to demonstrate the idea of tackling this research problem, and they cover the main development scope discussed earlier as well as other advanced modelling schemes for microfluidics and beyond.

Scientists and students working in the areas of MEMS and microfluidics will benefit from this book, which may serve both communities as both a reference monograph and a textbook for courses in numerical simulation, and design and development of microfluidic devices.

Contenu

List of Contributors. Foreword. Preface. Acknowledgements. Part I: 1. Literature Review for Micropumps. 1.1. Origins of Micropump Research. 1.2. Mechanical Micropumps. 1.3. Non-mechanical Micropumps. 1.4. Motivation. 2. Design Rules for Micropumps. 2.1. Preliminary Design. 2.2. Compression Ratio. 2.3. Criterion for Switching of Valve. 2.4. Criterion for Self-priming Capability. 2.5. Criterion for Bubble Tolerance. 3. Modelling and Simulation. 3.1. Background of Microfluidics Systems Modelling. 3.2. Governing Equation for Micro-pumps. 3.3. Modelling of the Actuator Unit. 3.4. Modelling of the Inlet Valve. 3.5. Modelling of the Outlet Valve. 3.6. System Model of Proposed Micro-pump. 4. Process Development and Fabrication. 4.1. Bulk Silicon Micromachining. 4.2. Process Flow. 5. Verification and Testing. 5.1. Experimental Set-up. 5.2. Piezoelectric Actuator Unit Model Verification. 5.3. Preliminary Functional Tests. 5.4. Conclusions And Recommendations. References. Appendices: Appendix A. Appendix B. Appendix C. Appendix D. Part II: 6. Development of Integrated Microfluidic Devices for Genetic Analysis; R.H. Liu, P. Grodzinski. 7. Microfluidic Devices on Printed Circuit Board; S. Richter, Nam-Trung Nguyen, A. Wego, L. Pagel. 8. Nano and Micro Channel Flows of Bio-Molecular Suspension; Fan Xijun, Nhan Phan-Thien, Ng Teng Yong, Wu Xuhong, Xu Diao. 9. Transport of Liquid in Rectangular Micro-Channels by Electroosmotic Pumping; Chun Yang. 10. A Development of Slip Model and Slip-Corrected Reynolds Equation for Gas Lubrication in Magnetic Storage Device; E. Yin-Kwee Ng, Ningyu Liu, Xiaohai Mao. 11. Short Notes on Particle Image Velocimetry for Micro/Nano Fluidic Measurements; Chee Yen Lim, F.E.H. Tay. Index.