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Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications.
The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis.
Microfluidic devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries.
Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores in detail a wide range of medical applications
Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies
Considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering
Échantillon de lecture
Woodhead Publishing Series in Biomaterials
Sterilisation of tissues using ionising radiations
Edited by J. F. Kennedy, G. O. Phillips and P. A. Williams
Surfaces and interfaces for biomaterials
Edited by P. Vadgama
Molecular interfacial phenomena of polymers and biopolymers
Edited by C. Chen
Biomaterials, artificial organs and tissue engineering
Edited by L. Hench and J. Jones
Medical modelling
R. Bibb
Artificial cells, cell engineering and therapy
Edited by S. Prakash
Biomedical polymers
Edited by M. Jenkins
Tissue engineering using ceramics and polymers
Edited by A. R. Boccaccini and J. Gough
Bioceramics and their clinical applications
Edited by T. Kokubo
Dental biomaterials
Edited by R. V. Curtis and T. F. Watson
Joint replacement technology
Edited by P. A. Revell
Natural-based polymers for biomedical applications
Edited by R. L. Reiss et al
Degradation rate of bioresorbable materials
Edited by F. J. Buchanan
Orthopaedic bone cements
Edited by S. Deb
Shape memory alloys for biomedical applications
Edited by T. Yoneyama and S. Miyazaki
Cellular response to biomaterials
Edited by L. Di Silvio
Biomaterials for treating skin loss
Edited by D. P. Orgill and C. Blanco
Biomaterials and tissue engineering in urology
Edited by J. Denstedt and A. Atala
Materials science for dentistry
B. W. Darvell
Bone repair biomaterials
Edited by J. A. Planell, S. M. Best, D. Lacroix and A. Merolli
Biomedical composites
Edited by L. Ambrosio
Drug-device combination products
Edited by A. Lewis
Biomaterials and regenerative medicine in ophthalmology
Edited by T. V. Chirila
Regenerative medicine and biomaterials for the repair of connective tissues
Edited by C. Archer and J. Ralphs
Metals for biomedical devices
Edited by M. Ninomi
Biointegration of medical implant materials: science and design
Edited by C. P. Sharma
Biomaterials and devices for the circulatory system
Edited by T. Gourlay and R. Black
Surface modification of biomaterials: methods analysis and applications
Contenu
Contributor contact details
Woodhead Publishing Series in Biomaterials
About the editors
Preface
Part I: Fundamentals of microfluidic technologies for biomedical applications
Chapter 1: Materials and methods for the microfabrication of microfluidic biomedical devices
Abstract:
1.1 Introduction
1.2 Microfabrication methods
1.3 Materials for biomedical devices
1.4 Polymers
1.5 Conclusion and future trends
1.7 Appendix: acronyms
Chapter 2: Surface coatings for microfluidic-based biomedical devices
Abstract:
2.1 Introduction
2.2 Covalent immobilization strategies: polymer devices
2.3 Covalent immobilization strategies: glass devices
2.4 Adsorption strategies
2.5 Other strategies utilizing surface treatments
2.6 Examples of applications
2.7 Conclusion and future trends
2.8 Sources of further information and advice
Chapter 3: Actuation mechanisms for microfluidic biomedical devices
Abstract:
3.1 Introduction
3.2 Electrokinetics
3.3 Acoustics
3.4 Limitations and future trends
Chapter 4: Digital microfluidics technologies for biomedical devices
Abstract:
4.1 Introduction
4.2 On-chip microdrop motion techniques
4.3 Sensing techniques
4.4 Future trends
4.5 Conclusion
Part II: Applications of microfluidic devices for drug delivery and discovery
Chapter 5: Controlled drug delivery using microfluidic devices
Abstract:
5.1 Introduction
5.2 Microreservoir-based drug delivery systems
5.3 Micro/nanofluidics-based drug delivery systems
5.4 Conclusion
5.5 Future trends
Chapter 6: Microneedles for drug delivery and monitoring
Abstract:
6.1 Introduction
6.2 Fabrication of microneedles (MNs)
6.3 MN design parameters and structure
6.4 Strategies for MN-based drug delivery
6.5 MN-mediated monitoring using skin interstitial fluid (ISF) and blood samples
6.6 Future trends
6.7 Conclusion
Chapter 7: Microfluidic devices for drug discovery and analysis
Abstract:
7.1 Introduction
7.2 Microfluidics for drug discovery
7.3 Microfluidics for drug analysis and diagnostic applications
7.4 Conclusion and future trends
7.5 Sources of further information and advice
Part III: Applications of microfluidic devices for cellular analysis and tissue engineering
Chapter 8: Microfluidic devices for cell manipulation
Abstract:
8.1 Introduction
8.2 Microenvironment on cell integrity
8.3 Microscale fluid dynamics
8.4 Manipulation technologies
8.5 Manipulation of cancer cells in microfluidic systems
8.6 Conclusion and future trends
8.7 Sources of further information and advice
Chapter 9: Microfluidic devices for single-cell trapping and automated micro-robotic injection
Abstract:
9.1 Introduction
9.2 Device design and microfabrication
9.3 Experimental results and discussion
9.4 Conclusion
9.5 Acknowledgements
Chapter 10: Microfluidic devices for developing tissue scaffolds
Abstract:
10.1 Introduction
10.2 Key issues and technical challenges for successful tissue engineering
10.3 Microfluidic device platforms
10.4 Conclusion and future trends
Chapter 11: Microfluidic devices for stem cell analysis
Abstract:
11.1 Introduction
11.2 Technologies used in stem cell analysis
11.3 Examples of microfluidic platform for stem cell analysis: stem cell culture platform - mimicking in vivo culture conditions in vitro
11.4 Examples of microfluidic platform for stem cell analysis: single stem cell analysis
11.5 Microdevices for label-free and non-invasive monitoring of stem cell differentiation
11.6 Microfluidics stem cell separation technology
11.7 Conclusion and future trends
Part IV: Applications of…