Lipid Metabolism in the Healthy and Disease Heart

Proceedings of the Third International Symposium on Lipid Metabolism in the Normoxic and Ischemic Heart, September 9 & 10, 1991, Rotterdam, The Netherlands

Contenu

Paradoxical role of lipid metabolism in heart function and dysfunction.- Interrelationship between lactate and cardiac fatty acid metabolism.- Dietary modulation of lipid metabolism and mechanical performance of the heart.- The substrate specificity of phosphoinositide-phospholipase C in rat heart sarcolemma.- Long term incubation of cardiac myocytes with oleic acid and very-low density lipoprotein reduces heparin-releasable lipoprotein lipase activity.- Carnitine palmitoyltransferase in the heart is controlled by a different mechanism than the hepatic enzyme.- Myocardial cell vulnerability to exogenous phospholipase attack.- Phosphatidylcholine metabolism in ischemic and hypoxic hearts.- Occurrence and functions of the phosphatidylinositol cycle in the myocardium.- Modulation of phosphatidylethanolamine biosynthesis by exogenous ethanolamine and analogues in the hamster heart.- Eicosapentaenoic and docosahexaenoic cultured rat ventricular myocytes and hypoxia-induced alterations of phospholipase-A activity.- Incorporation of radioiodinated fatty acids into cardiac phospholipids of normoxic canine myocardium.- Kinetic changes of ethanolamine base exchange activity and increase of viscosity in sarcolemmal membranes of hamster heart during development of cardiomyopathy.- Annexins in cardiac tissue: cellular localization and effect on phospholipase activity.- Myocardial fatty acid oxidation during ischemia and reperfusion.- The relative contribution of glucose and fatty acids to ATP production in hearts reperfused following ischemia.- Effects of palmitoyl CoA and palmitoyl carnitine on the membrane potential and Mg2{+} content of rat heart mitochondria.- Carnitine requirement of vascular endothelial and smooth muscle cells in imminent ischemia.- Protection of the ischemic diabetic heart by L-propionylcarnitine therapy.- Functional and metabolic effects of propionyl-L-carnitine in the isolated perfused hypertrophied rat heart.- L- propionylcarnitine and myocardial performance in stunned porcine myocardium.- Release of heart fatty acid-binding protein into plasma after acute myocardial infarction in man.- Regulatory functions of the coronary endothelium.- Lipid metabolism of myocardial endothelial cells.- Endothelium, the dynamic interface in cardiac lipid transport.- Malondialdehyde is a biochemical marker of peroxidative damage in the isolated reperfused rat heart.- Studies on the interaction of leucocytes and the myocardial vasculature. I. Effect of hypoxia on the adherence of blood granulocytes.- Arachidonic acid incorporation in cardiomyocytes, endothelial cells and fibroblast-like cells isolated from adult rat heart.