Microneedles explores the design, fabrication and use of microneedles for drug and vaccine delivery. This book discusses the contemporary status of the field, describing several areas in detail, including the distinct types of microneedles (dissolving, solid, coted, hollow and hydrogel-forming). The anatomy of the eye is also described to facilitate an understanding of microneedle-assisted ocular drug delivery. Finally, the book provides a detailed discussion of microneedle use in the field of diagnostics, with a chapter dedicated to the mathematical modeling of microneedle-mediated drug delivery.

As microneedles can be used by research scientists in academia and in industry, this book will be ideal for regulatory scientists and graduate students who find the topic relevant to their area of study.

Provides information for the design and fabrication of microneedles
Discusses choice of materials, fabrication protocol, sterilization protocol and characterization
Supplies the most up-to-date research on all aspects of microneedles

Auteur

Dr. Ita holds a PhD in Pharmaceutics. His area of expertise is transdermal drug delivery. He has over 40 publications in this area and teaches Pharmaceutics to both first- and second year pharmacy students at the College of Pharmacy, Touro University, California. He joined the University in 2006 as an Assistant Professor and is now a Full Professor. He was awarded an ICRETT Fellowship by the International Union Against Cancer (IUCC).

Contenu

Introduction
1. Fabrication of Microneedles
2. Dissolving Microneedles
3. Anatomy and Physiology of the Eye
4. Microneedle-Assisted Drug Delivery to the Eye
5. Microneedles for Diagnostic Testing
6. Therapeutic Drug Monitoring with Microneedles
7. Miscellaneous Routes of Microneedle-Assisted Drug Delivery
8. Mathematical Modeling of Drug Delivery from Microneedles
9. Solid Microneedles
10. Coated Microneedles
11. Hollow Microneedles
12. Hydrogel-forming Microneedles