Intercellular Signalling in the Mammary Gland

All being done, we went to Mrs Shipmans, who is a great butter-woman; and I did see there the most of milke and cream, and the cleanest, that I ever saw in my life (29 May 1661). Among others, Sir Wm. Petty did tell me that in good earnest, he hath in his will left such parts of his estate to him that could invent such and such things -as among others, that could discover truly the way of milk coming into the breasts of a woman ... (22 March 1665). My wife tells me that she hears that my poor aunt James hath had her breast cut off here in tow- her breast having long been out of order (5 May 1665). From the Diary of Samuel Pepys, published as The Shorter Pepys (edited by R. Latham), Penguin Books (1987) The long-standing ultimate importance of research on the mammary gland is illustrated by the importance attached to cows' milk for human consumption, to human lactation and to breast cancer by Samuel Pepys and his contemporaries in the middle of the 17th century. Research has tended to develop in isolation in these three areas of continuing contemporary importance largely because in most countries, the underlying science of agricultural productivity is funded separately from the underlying science of human health and welfare.

Contenu

Mammary Development: Growth and Growth Factors: The Environment of the Mammary Secretory Cell (C.H. Knight). Role of Bovine Placental Lactogen in Intercellular Signalling during Mammary Growth and Lactation (R.J. Collier et al.). Expression of Hox Genes in Normal and Neoplastic Mouse Mammary Gland (Y. Friedmann, C.W. Daniel). Apoptosis in Mammary Gland Involution: Isolation and Characterization of Apoptosisspecific Genes (W. Bielke et al.). Mammary Development: Differentiation and Gene Expression: Extracellular Matrix Dependent Gene Regulation in Mammary Epithelial Cells (C. Schmidhauser et al.). Regulation of Milk Secretion and Composition by Growth Hormone and Prolactin (D.J. Flint). Basement Membrane in the Control of Mammary Gland Function (C.H. Streuli). Heterogeneous Expression and Synthesis of Human Serum Albumin in the Mammary Gland of Transgenic Mice (I. Barash et al). Milk Secretion: Autocrine Control of Milk Secretion: Development of the Concept (M. Peaker). Endocrine and Autocrine Strategies for the Control of Lactation in Women and Sows (P.E. Hartmann et al.). Autocrine Control of Milk Secretion: From Concept to Application (C.J. Wilde et al.). A Role for Mediumchain Fatty Acids in the Regulation of Lipid Synthesis in Milk Stasis? (D.H. Williamson et al.). 41 additional articles. Appendix. Index.