Inflammatory and Infectious Basis of Atherosclerosis

In the last ten years, major strides have been made in defining the presence and role of inflammation in atherosclerosis as well as in injury to the tissues that occurs after episodes of ischemia and reperfusion. In sixteen chapters, written by world-renowned individuals from different countries, the role of inflammation and different mediators in the pathogenesis of atherosclerosis is presented. The significance of inflammation and possible therapeutic implications is also described in depth. This book is of great interest for a wide range of physicians, researchers, and scientists who may want to study more and develop the concept of inflammation and atherosclerosis.

Contenu

Atherosclerosis: an inflammatory disease.- Inflammation in coronary atherosclerosis - pathological aspects.- Pathology of acute coronary syndromes.- Transplantation-associated arteriosclerosis and inflammation.- Free radicals as mediators of inflammation in atherosclerosis.- Myocardial reperfusion: a state of inflammation.- LOX-1, a potential inflammatory mediator in atherosclerosis.- Angiotensin II as a mediator of inflammation in atherosclerosis.- Role of interleukins in relation to the renin-angiotensin-system in atherosclerosis.- Heme oxygenase-1, inflammation and atherosclerosis.- Lymphocyte activation in acute coronary syndromes.- Role of infection in atherosclerosis and precipitation of acute cardiac events.- C-reactive protein - a prognostic marker of inflammation in atherothrombosis.- Inflammation as a marker of outcome in myocardial ischemia.- Antibiotics in the prevention of coronary heart disease: review of the randomised trials.- Fish oil - a potential therapy for inflammatory atherosclerosis.