Immunonutrition

The interaction of immune function and nutrition underlies the low-grade chronic inflammation involved in the etiology of many common obesity-associated and age-related chronic disease conditions. This book introduces the breadth of the new field of immunonutrition, which implicates nutrition in both immune function and in the etiology, prevention, and treatment of common diseases influenced by inflammation and immune imbalance, including obesity, diabetes, heart disease, asthma, autoimmune diseases, and common forms of cancer. The book addresses the basic mechanisms of immunity, immunonutrition-related diseases, and potential nutrition-based treatments.

Auteur

David Heber, MD, PhD, FACP, FACN, is the director of the UCLA Center for Human Nutrition at the University of California, Los Angeles. He has been on the faculty of the UCLA School of Medicine since 1978 and is currently professor of medicine and public health. Dr. Heber is board certified in internal medicine and endocrinology and metabolism by the American Board of Internal Medicine and is certified as a physician nutrition specialist. He is a former chair of the Medical Nutrition Council of the American Society of Nutrition. He has written more than 230 peer-reviewed scientific articles and 60 book chapters, as well as three professional texts. He has written four books for the public, including What Color Is Your Diet? (Harper Collins/Regan Books, 2001) and the L.A. Shape Diet (Harper Collins/Regan Books, 2004). His main research interests are obesity prevention and treatment and phytonutrients in cancer prevention and treatment.

Bharat B. Aggarwal, PhD, is a Ransom Horne, Jr. Distinguished Professor of Cancer Research, Professor of Cancer Medicine, Professor of Immunology, Professor of Biochemistry, and Professor of Experimental Therapeutics, as well as Chief, Cytokine Research Section, in the Department of Experimental Therapeutics at the University of Texas MD Anderson Cancer Center, Houston. He has been investigating the role of inflammatory pathways mediated through TNF, NF-kappaB, and STAT3 for the prevention and therapy of cancer and other chronic diseases. While searching for novel and safe anti-inflammatory agents, his group has identified more than 50 novel compounds from dietary sources and from traditional medicine, some of which are now in clinical trials. Dr. Aggarwal has published more than 600 papers in peer-reviewed international journals (including Science, Nature, Cancer Cell, Blood, and Cancer Discovery), invited reviews, book chapters, and a book entitled Healing Spices (released

Contenu

Evolution of Innate and Adaptive Immunity. Cellular Mechanisms of Cytokine Activation. Cellular Lipids and Inflammation. Biomarkers of Inflammation and the Western Diet. Phytochemicals and Immune Function. Genetic and Environmental Modifiers of Immune Function. Cancer and Inflammation. Abdominal Obesity: Pathophysiology and Related Metabolic. Complications. Type 2 Diabetes and Inflammation. Heart Disease and Inflammation. Chronic Kidney Disease and Inflammation. Alzheimer's Disease and Inflammation. Nutrition in Autoimmunity: A Focus on Systemic Lupus. Erythematosus and Rheumatoid Arthritis. Asthma and Inflammation. Muscle and Immune Function. Approaches to Reducing Abdominal Obesity. Barriers to Fruit and Vegetable Consumption and Practical. Strategies for Increasing Fruit and Vegetable Intake. Healthy Fats and Oils: Balancing Omega-3 and Omega-6 Acids in Tissues. Spices and Dietary Supplements with. Anti-Inflammatory Activity.