Aharon Katzir Memorial Volume

It was a warm, sunny morning in Rehovot. The sky was c1ear as it always is in June. As I walked to the Institute that morning, too many cars were passing by, too many people were hurrying onto the Institute's grounds. No one was smiling, acquaintances were recognized by a slight nod of the head. When I turned the corner, a few people already had gathered on the lawn in front of the Jacob Ziskind building. This number was to swell to thousands before the service was over. We were to be joined by the President of Israel, its first Prime Minister, many members of the cabinet, and other great, near-great, working colleagues, and residents of the town. The purpose of all this activity was written on everyone's face, and underlined by the casket that lay in the rotunda of the building. His wife was sitting there, his children, his brother, his students both past and present. One could hear the silence of the participants. I stood inside for a while, overlooking the rotunda. A long line of mourners filed by, offering their sympathies to the family. Suddenly a woman, dressed in black, fell to her knees in front 9f Rina, sobbing. It was the wife of the Japanese Ambassador to Israel. I moved to join the crowd outside. People were standing on the lawn, gingerly trying to avoid stepping on a flower.

Contenu

1 Fluidity and Phase Transitions of Cell Membranes.- I. Introduction.- II. Phase Transitions and Fluidity of Lipid and Membrane Systems.- III. Triggering Mechanisms.- IV. Conclusions.- References.- 2 Criteria in Carrier Transport.- I. Introduction.- II. Criteria for Diffusion.- A. Fick's Diffusion Law.- B. The Flux Ratio.- III. Carrier-Mediated Transport.- A. Low Saturation.- B. General Case. Flux Ratio.- C. High Saturation.- D. Counter Transport.- E. Other "Exchange" Phenomena.- F. Comparative Considerations.- IV. Active Transport.- A. Uphill Operation.- B. Dependence on Metabolism.- C. Short Circuit Current.- D. Asymmetric Michaelis Constants.- E. The Flux Ratio Criterion of Ussing.- V. Conclusion.- References.- 3 Carotenoid and Merocyanine Probes in Chromatophore Membranes.- I. Introduction.- II. Materials and Methods.- A. Experimental Methods.- B. Preparations.- C. Merocyanine Probes.- D. Binding Determinations.- E. Energy Transfer between Chlorophyll, Carotenoid, and Merocyanine Probes.- III. Experimental Results.- A. Responses to Steady State Illumination.- B. Kinetic Responses.- IV. Discussion.- A. Location of the Probes.- B. Energy Transfer between Chlorophyll, Carotenoid, and Merocyanine Probes.- C. Response of Merocyanine to Valinomycin-Stimulated K+ Diffusion.- D. Responses to Flash Illumination of Chlorophyll, Carotenoid, and Merocyanine.- E. Electrochromic Responses.- References.- 4 Effects of Sulfhydryl Reagents on Basal and Vasopressin-Stimulated Na+ Transport in the Toad Bladder.- I. Introduction.- II. Materials.- III. Methods.- A. Short-Circuit Current Experiments.- B. Assay of Soluble SH Compounds.- C. Effects of Amiloride on Titratable SH Groups.- D. Effects of Vasopressin on Titratable SH Groups.- IV. Results.- A. Penetration of SH Reagents into Toad Bladder Epithelium.- B. Effects of SH Reagents on SCC.- C. Effects of Amiloride on Titratable SH Groups.- D. Effects of Vasopressin on Titratable SH Groups.- V. Discussion.- VI. Summary.- References.- 5 Biogenesis of Chloroplast Membranes in Chlamydomonas Reinhardi: Chloroplast-Controlled Transfer of Cytoplasmic Proteins As Visualized by Quantitative Radioautography.- I. Introduction.- II. Materials and Methods.- A. Radioactive Labeling and Autoradiography.- B. Chemical Determinations.- III. Results.- IV. Discussion.- V. Summary.- References.- 6 Nerve Excitability-Toward an Integrating Concept.- I. Integral Physicochemical Mode for Nerve Excitation.- A. Introduction.- B. Stationary Membrane Potentials.- C. Transient Changes of Membrane Properties.- D. The Cholinergic System and Excitability.- E. The Integral Model.- II. Biochemical Foundation of the Integral Model.- A. Cell Membranes.- B. Chemical Hypothesis of Excitability.- C. Macromolecular Conformation and Ca2+ Ions.- III. Synaptic Transmission.- A. Problem of the Role of AcCh at Junctions.- B. Early Observations That Suggested a Special Function of AcCh at Synaptic Junctions.- C. Evidence Supporting a Similar Role of AcCh Cycle in Pre- and Postsynaptic Junctional Membranes.- D. Alternative Interpretation of the Function of AcCh at Junctions.- IV. Concluding Remarks.- V. Summary.- References.- 7 Peptide Transport.- I. Introduction.- II. Methods of Studying Peptide Transport.- A. Direct Methods.- B. Indirect Methods.- III. Peptide Transport and Peptidases.- A. Bacteria.- B. Yeast.- C. Mammals.- D. Conclusions.- IV. The Properties of Peptide Transport Systems.- A. Bacteria.- B. Yeast.- C. Mammals.- D. Summary.- References.- 8 Factors Influencing the Retention of K in a Halobacterium.- I. Outside KCl Concentration.- A. Introduction.- B. Materials and Methods.- C. Results.- D. Discussion.- E. Summary.- II. pH and Nature and Concentration of Salt in Outside Medium.- A. Introduction.- B. Materials and Methods.- C. Results.- D. Discussion.- E Summary.- References.