Stress in Health and Disease

Stress in Health and Disease presents the principal pathways mediating the response to a stressor. It discusses the clinical background of cross-resistance and treatment with stress-hormones. It addresses the diseases of adaptation or stress diseases, diagnostic indicators, and functional changes.
Some of the topics covered in the book are the concept of heterostasis; stressors and conditioning agents; morphology of frostbite; characteristics manifestations of stress; catecholamines and their derivatives; various hormones and hormone-like substances; FFA, triglycerides and lipoproteins; morphologic changes; and hypothalamo-hypophyseal system . The gastrointestinal diseases of adaptation are covered. The schizophrenia and related psychoses is discussed. The text describes the manic-depressive disease and senile psychosis. A study of the experimental cardiovascular diseases and neuropsychiatric diseases is presented. A chapter is devoted to the diseases of adaptation in animals. Another section focuses on the shift in adenohypophyseal activity and catatoxic hormones.
The book can provide useful information to scientists, doctors, students, and researchers.

Contenu

Foreword

Purpose and Scope

Prefatory Remarks on the Style of this Book

General Structure

References

Critique and Personal Observations

Reviews

Our Earlier Stress Monographs

General

Popular

Foreign Languages

How to Use This Book

Glossary

Stress Tests

I. History and General Outline of the Stress Concept

History

Prescientific Intuitive Feelings Foreshadowing the Existence of Stress

Beginnings of a Scientific Analysis

The General Adaptation Syndrome (G.A.S.)

General Outline

Definition and Terminology of Biologic Stress

Principal Pathways Mediating the Response to a Stressor

Conditioning

Degrees of Specificity, Relationship between the G.A.S

and L.A.S

Cross Resistance and Treatment with Stressors or Stress Hormones

The Diseases of Adaptation or Stress Diseases

Syntoxic and Catatoxic Responses

The Concept of Heterostasis

Behavioral Implications

II. Stressors and Conditioning Agents

Trauma

Generalities

ACTH and Corticoids

Catecholamines (EP, NEP)

STH

Insulin

Sex Hormones

Other Hormones

Histamine and 5-HT

Enzymes

Other Metabolites

Other Targets

• Age

• Anesthesia

• Temperature

• Season

• Diet

• Genetics

  Drugs

  AMP, ADP, ATP

  Alloxan

  Aminoglutethimide

  Amphenone

  Anesthetics and Analgesics

  Antiadrenergics

  Antibiotics

  Anticholinergics

  Antihistamines

  Asiaticoside

  Benzol

  Cannabis

  Chlorpromazine

  CNS Stimulants

  Colchicine

  Cysteamine

  DDD

  DDT

  DNA, RNA

  Dibenzyline

  Diphenylhydantoin

  DMSO

  DOPA

  Electrolytes, Water, Osmotic Pressure

  Ethanol

  Ethionine

  a-Ethyltryptamine, a-Methyltryptamine

  Formaldehyde

  Glucose

  6-Hydroxydopamine

  Insecticides

  Isethionate

  MAO Inhibitors

  Meprobamate

  Methadone

  Methamphetamine

  Metrazol

  Metyrapone (Metopirone)

  Morphine

  a-MT

  Mustards

  Narcotics and Other Psychotropic Drugs

  Nialamide

  Nicotine

  Nicotinic Acid

  Nitrous Oxide

  PCPA

  Pimozide

  Poly chlorinated Biphenyls

  Psychotropic Drugs

  Reserpine

  Ricin

  Salicylates

  Tranquilizers

  Vitamins

  Various Drugs or Drug Combinations Not Previously Mentioned

  Hormones and Hormone-like Substances

  Catecholamines

  Corticoids

  Glucagon

  Gonadotropic and Gonadal Hormones

  Histamine and 5-HT

  Insulin

  Pineal Hormones

  Renin, Angiotensin

  STH

  Thymus Hormones

  Thyroid Hormones

  Vasopressin.

  Diet

  Generalities

  Hormones

  Varia

• Temperature Variations

• Restraint

• Other Stressors

  Physical Agents

  Temperature, including Frostbite

  Burns

  Sound

Ultrasound, Sonic Booms

Ionizing Rays

Light Rays

Ultraviolet Rays

Vibration

Air Blasts

Compression, Decompression

Gravity

Electricity, Electroshock

Magnetism

Osmotic Pressure

Microorganisms and Their Toxins

Generalities

Hormones

• Varia

  Immunity

  Hypoxia, Decreased Barometric Pressure including Hyperbaric Oxygenation

  Generalities

  Morphology

  Hormones

  Enzymes and Other Metabolites

  Nervous Changes

  Varia

• Varia

  Hemorrhage

  Muscular Exercise

  Generalities

  Hormones

  Enzymes and Other Metabolites

• Varia

  Restraint

  Generalities

  Hormones

  Enzymes and Other Metabolites

  Varia

• Varia

  Athletics

  Generalities

  Hormones

• Varia

  Neuropsychologic Stimuli

  Generalities

  Pain and Grief

  Anxiety, Anticipation, Fear, Arousal

  Public Speaking

  Sleep Deprivation

  Motivation

  Cognition

  Fighting, Anger, Hate

  Sensory Deprivation, Boredom, Monotony

  Pleasure

  Handling and Gentling

  Varia

  Climate, Environment

  Generalities

  Pollution

  Social, Cultural, Family

  Crowding

  Isolation

  Captivity

  Concentration Camps, POWs

  Relocation and Travel

  Urbanization

  Catastrophe, Accidents

  Biorhythms

  Circadian

  Seasonal Variations

  Hibernation

  Meteorologic Influences

  Occupation

  Aerospace

  Parachute Jumping

  Air Traffic Control

  Navy, Marine, Submarine

  Diving

  Military Life, including Combat

  Automobile Driving

  Industry, Labor, Business, Finance

  Executive Life

  Medicine, Dentistry, Nursing

  Law

  Police Work

  Shift Work

  Telephone and Telegraph Operators

  Various Other Occupations

  Unemployment, Retirement

  Physiologic States

  Age

  Sex (Including the Sexual Cycle)

  Pregnancy and Lactation

  Genetics, Race, Constitution

  Generalities

  Vertebrates

  Mammals

  Birds

  Reptiles

  Amphibians

  Fish

  Invertebrates

  Plants and Microorganisms

  Tumors

  Combined Effect of Various Agents

  Multiple Stressors (Cross-resistance and Cross-sensitization)

III. Characteristic Manifestations of Stress

Chemical Changes

Body Weight

Basal Metabolic Rate (BMR)

Other Metabolites

Morphologic Changes

Hypothalamo-hypophyseal System

Adrenals

Thyroid

Sex Organs (including Pregnancy and Lactation)

Pancreas

Pineal Gland

Thymicolymphatic and Hematopoietic Organs

Blood Cells, Blood Volume

Cardiovascular System

Gastrointestinal System

Oral (Teeth, Periodontal) Structures

Salivary Glands

Lung

Ocular Structures

Kidney

Liver

Connective Tissue, Wound Healing, Regeneration and Inflammation

Skin

Reticuloendothelial System (RES)

Tumors

Other Morphologic Changes

Functional Changes

Resistance

Nervous System

Stress Tests

Body Temperature

Cardiovascular System, including Blood Pressure, ECG

Muscular System

Blood Coagulation

Immunology

Death

Varia

IV. Diseases of Adaptation

Generalities

Shock

Gastrointestinal Diseases of Adaptation

Peptic Ulcers

Experimental Peptic Ulcers

Ulcerative Colitis

Varia

Cardiovascular Diseases (including Hypertension, Cardiac Infarcts, Periarteritis Nodosa)

Generalities

History

Stressors in Ge…