Gonadotropins and Gonadal Function

Gonadotropins and Gonadal Function presents the proceedings of the International Symposium on the Advances in Chemistry, Biology and Immunology of Gonadotropins, held at the Indian Institute of Science, Bangalore, India in October 1973.

The book reviews the chemistry, physiology and biochemical mechanism of action of gonadotropins. The compendium is divided into four sections. Section I discusses the chemistry of gonadotropins. Section II covers the biology and immunology of gonadotropins. The third section tackles the biochemistry of gonadotropins. The final section presents gonadotropins in clinical medicine.

Endocrinologists, physicians, biochemists, and medical researchers will find the book highly interesting.

Contenu

List of Contributors
Foreword
Preface
List of Abbreviations
Section I. Chemistry of Gonadotropins
On the Chemistry of Pituitary Interstitial Cell Stimulating Hormone
Structural Study of Luteinizing Hormone
Chemistry of Follicle Stimulating Hormone
Chemical Aspects of Highly Purified Human Pituitary Follicle Stimulating Hormone
Characterization of Ovine Pituitary Glycoprotein with Dual Gonadotropic Activity
Purification and Characterization of Urinary hCG
Chemistry of Human Chorionic Gonadotropin
Purification and Characterization of Human Chorionic Gonadotropin in Hydatidiform Mole
Identification and Chemical Characterization of the Pituitary Gonadotropins in Reptiles and Amphibians
Some Aspects of Chemistry and Biology of Piscine Gonadotropins
Studies on Hypothalamic Gonadotropin-Releasing Factors
Recent Advances in the Physiology and Chemistry of Gonadotropin-Releasing Factors
Section II. Biology and Immunology of Gonadotropins
Gonadotropins: A Correlation of Biological and Immunological Activities
Immunosorbents of Gonadotropins and Their Antibodies
The Use of Granulosa Cell Cultures and Short-Term Incubations in the Assay for Gonadotropins
Gonadotropic Control of the Development of Testes and Accessory Organs
Gonadotropin Regulation of Follicular Development in the Hamster
Studies on Follicular Maturation - Effects of FSH- and LH Antisera in Hamsters
Gonadotropins and Functions of Granulosal and Thecal Cells In Vivo and In Vitro
Role of Gonadotropins in Ovulation
Effect of Anti-Gonadotropin Serum on Ovulation in Mice
Luteotropic Complex in Lactating Rats
Role of Luteinizing Hormone and Prolactin in the Luteotropic Process
Ultrastructural Changes in the Corpus Luteum of Pregnancy in the Golden Hamster following LH Deprival
Section III. Biochemistry of Gonadotropins
Mechanism of Action of Luteinizing Hormone - Releasing Hormone
Hypothalamic Content of Luteinizing Hormone Releasing Factor and Its Mechanism of Action on the Rat Anterior Pituitary
Biosynthesis of Gonadotropins and Their Releasing Factors
Chorionic Gonadotropin Produced from the Cultivated Trophoblast
Interactions between Prostaglandins and Gonadotropins on Corpus Luteum Function
Evidence for the Role of Ovarian Prostaglandins in Ovulation
Possible Role of Prostaglandins in the Secretion of Gonadotropins
Gonadotropins and Cyclic AMP in Various Compartments of Rat Ovary
The Role of Cyclic AMP and Prostaglandins in the Actions of Luteinizing Hormone
Studies on the Mechanism of Action of LH
The Role of Cytochrome P.450 in the Side-Chain Cleavage of Cholesterol
Gonadotropin-Receptor Activity and Granulosa Luteal Cell Differentiation
Studies on Action of Luteinizing Hormone in the Rat
Purification of LH-HCG Receptor from Luteinized Rat Ovaries
The Role of Carbohydrate in t h e Biological Function of Human Chorionic Gonadotropin
Biochemical Aspects of the Interaction of the Human Chorionic Gonadotropin with Rat Gonads
Some Effects of FSH on t h e Seminiferous Epithelium of Mammalian Testis
Cell-Types Influenced by FSH in the Rat Testis
Section IV. Gonadotropins in Clinical Medicine
Induction of Ovulation with Gonadotropins: Prevention of Ovarian Hyperstimulation
Use of Urinary Estrone and Other Parameters in Monitoring Gonadotropin Therapy
Regulation of Gonadal Function in the Male by Gonadotropins
Serum Gonadotropins in Men with Hypogonadism: Mesterolone in the Treatment of Oligozoospermia
Concluding Remarks
Subject Index