Gonadotropic Hormones

Hormonal Proteins and Peptides, Volume XI: Gonadotropic Hormones deals with gonad stimulating hormones that cause precocious sexual maturity.

This book begins by reviewing the relationship of the chemical structure to the biological activity of gonadotropins and chorionic hormones, followed by a brief presentation on the in vitro bioassay methods. A comprehensive discussion on some aspects of the molecular mechanism of gonadotropin action is also provided. This publication concludes with an analysis of the immunobiology of gonadotropins.

This book is intended for endocirnologists, but is also useful for medical practitioners and researchers concerned with gonadotropic hormones.

Contenu

Contributors
Preface
Contents of Previous Volumes
1 Gonadotropic Hormones: Relationship between Structure and Function with Emphasis on Antagonists
I. Introduction
II. Isolation and Characterization
III. Subunit Nature
IV. The Polypeptide Structure
V. Structure-Function Relationships
VI. Subunit and Receptor Interaction Site Mapping
VII. Role of the Carbohydrate Moiety
VIII. Antigonadotropic Substances: What Are They?
IX. Structure-Function Changes Induced by Steroids
X. Biological Properties of Subunits
XI. Concluding Remarks
References
2 In Vitro Methods of Gonadotropin Assay
I. Introduction
II. Bioassay of Lutropin
III. Applications of the Leydig Cell Assay
IV. Bioassay of Follitropin
V. Applications of the in Vitro Follitropin Assay
VI. Concluding Remarks
References
3 Some Observations and Commentary on the Mechanism of Action of Gonadotropins
I. Introduction
II. Gonadotropin Binding to Receptors
III. Regulation of Adenylate Cyclase
IV. Protein Kinase
References
4 Advances in Immunobiology of Gonadotropins
I. Introduction
II. Immunology of Gonadotropins
III. Actions of Gonadotropins in the Ovary
IV. Involvement of Gonadotropins in Testicular Function
V. Gonadotropin Antibodies as Antifertility Agents
References
Index