Electrophysiological Methods

Physical Techniques in Biological Research Volume VI: Electrophysiological Methods presents the analytical methods and experimental techniques in electrophysiological research. It discusses the handling and analysis of information by computer methods. It addresses the methods of analysis of waveforms, signal characterization and detection.
Some of the topics covered in the book are the fundamentals of digital and analog computers; analysis of complex waveforms; operational amplifiers; signal processing and parameter estimation; the core conductor model; voltage clamp techniques; cable theory; automatic computation equipment; and electric accounting machinery. The wave shape generation are covered. The characterization of systematic functions is discussed. The text describes the nerve containing axial wire. A study of the internal thin and outer diffuse electrodes is presented. A chapter is devoted to the simple one dimensional model. Another section focuses on the cylindrical model with radial symmetry and accuracy of membrane potential measurement.
The book can provide useful information to experimenters, students, and researchers.

Contenu

Contributors to Volume VI
Preface to Volume VI
Contents of Volumes I, II, III, IV, and V
List of Abbreviations

1. Fundamentals of Digital and Analog Computers
   I. Introduction
   II. Electric Accounting Machinery
   III. Digital Computers
   IV. Analog Computers
   V. Hybrid Computation: Combining Analog and Digital Techniques
   VI. Applications of Computers
   References
2. Operational Amplifiers
   I. Introduction
   II. General Properties
   III. Limitations
   IV. Examples of Use
   References
3. Analysis of Complex Waveforms
   I. Introduction
   II. Signal Characterization
   III. Signal Processing and Parameter Estimation
   IV. Signal Detection
   V. Experimental Techniques
   References
4. Cable Theory
   I. Introduction
   II. The Core Conductor Model
   III. More Complicated Geometries
   IV. Further Useful Relations
   V. Concluding Remarks
   List of Symbols and Definitions
   References
5. Voltage Clamp Techniques
   I. Introduction
   II. Definition and Criterion
   III. Method of Control
   IV. Experimental Requirements
   V. Equipment: Description and Performance
   References
6. Determination of Biological Impedances
   I. Introduction and Fundamentals
   II. Electrode Polarization
   III. Measurements at Low Frequencies
   IV. Measurements at Radio Frequencies
   V. Measurements at Very High Frequencies
   References
   Author Index
   Subject Index