Electrophysiological Methods

Electrophysiological Methods presents a compilation of essays relating to the field of electricity. One topic is the introduction and analysis of electrical stimulation. Other types of stimulation are thermal stimulation, light stimulation, touch stimulation, and auditory stimulation. Microelectrodes act as links by which small regions in biological tissues are electrically joined to amplifying and recording devices. This topic is explored more thoroughly in the book.
The physiological activity of cells in nerves, muscles, secretory organs, and other biological structures is accompanied by electrical changes which appear across the cell membrane. This occurrence is another topic in the text. Intracellular techniques employed to record transmembrane potentials and to stimulate cells are likewise presented. A section of the book presents microelectrophoresis which is a method wherein electrical flow is employed to manipulate the ejection of chemical substances from fine microelectrodes or micropipettes.
The book will provide useful information to neurologist, cytologist, doctors, students, and researchers in the field of medicine.

Contenu

Contributors to Volume
Preface to Volume V
Contents of Volumes I, II, III, IV, and VI
List of Abbreviations

1. Stimulation
   I. Introduction
   II. Electrical Stimulation
   III. Stimulation of Special Receptors
   References
2. Microelectrodes for Recording and Stimulation
   I. Introduction
   II. Metal Electrodes
   III. Glass Micropipette Electrodes
   IV. Electrical Properties of Glass Microelectrodes
   V. Circuits Used in Applying Microelectrode Techniques
   VI. Microelectrode Application
   References
3. Electrodes for Extracellular Recording and Stimulation
   I. Introduction
   II. Definitions and Preliminary Remarks
   III. Some Fundamental Characteristics of the Electrodes Used in Biological Research
   IV. Recording of Electrical Activity
   V. Electrical Stimulation of Excitable Tissues
   VI. Preparation and Use of Electrodes
   References
4. Microelectrophoresis
   I. Introduction
   II. Basic Principles
   III. Practical Considerations
   IV. Practical Applications and Advantages of the Technique
   V. Difficulties Associated with the Technique Addendum: Microinjection (R. D. Keynes)
   References
5. Micromanipulators: Principles of Design, Operation, and Application
   I. General Micrurgical Problems
   II. Optical Considerations
   III. Microscope Stands
   IV. Low Magnification Micromanipulators
   V. High Magnification Micromanipulators
   VI. Microinjectors
   VII. Integrated Micromanipulator-Microinjector Assemblies
   VIII. Future Trends in Micromanipulator Design
   References
6. Transducers
   I. Introduction
   II. Transducers for Mechanical Input
   III. Temperature Transducers
   IV. Transducers for Electrical Input
   V. Optical Transducers
   VI. Nuclear Radiation Transducers
   References
7. Bioelectric Amplifiers
   I. General Requirements of Bioelectric Amplifiers
   II. Amplifier Circuits
   III. Feedback in Amplifiers
   References
8. Interference and Its Elimination
   I. Introduction
   II. Theory of Interference and Elimination
   III. Practical Elimination of Electrical Interference
   IV. Reduction of Mechanical Interference
   V. Caution
   VI. Addendum: Destructive Interference
   References
9. Recording and Display
   I. Introduction
   II. Factors Influencing the Fidelity of a Recorder
   III. Characteristics of Moving-Coil Galvanometers
   IV. Servo Recorders
   V. Cathode Ray Oscilloscope Recorders
   VI. Magnetic Tape Recorders
   VII. Digital Devices
   VIII. Other Display Techniques
   IX. Recording and Noise
   References
   Author Index
   Subject Index