Control of Breathing during Sleep

This book describes control of ventilation during sleep in both health and disease states. The topics are presented in a fashion that can be easily comprehended with many figures to illustrate complex concepts.

Auteur

Dr. Susmita Chowdhuri, M.D., M.S. is a Professor of Internal Medicine at Wayne State University School of Medicine and a Staff Physician and the Section Chief of Sleep Medicine at the John D. Dingell VA Medical Center in Detroit, Michigan.

Dr. M. Safwan Badr, M.D., M.B.A. is a Professor and Chair of Internal Medicine at Wayne State University School of Medicine and a Staff Physician at the John D. Dingell VA Medical Center.

Dr. James A Rowley is a Professor of Medicine and Division Chief of Pulmonary/Critical Care and Sleep mMdicine at Wayne State University School of Medicine in Detroit, Michigan.

Contenu

TABLE OF CONTENTS

Section I. Anatomy, development, aging and mechanisms of control of ventilation

Chapter 1 Anatomy of the Respiratory Neural Network Christopher A. Del Negro, PhD and Christopher G. Wilson, PhD

Chapter 2 Chemoreception: Pathways, Plasticity, and Pathophysiology Barbara J. Morgan, PhD and Jerome A. Dempsey, PhD

Chapter 3 Developmental changes in the Respiratory System of the Neonate-Child Ahuva Brown, Liran Tamir Hostovsky, Estelle B. Gauda

Chapter 4 Control of Breathing in Older Adults Susmita Chowdhuri, MD, MS

Chapter 5 Breathing Control in Exercise Philippe Haouzi

Chapter 6 Control of the Upper Airway during Sleep Lezek Kubin, PhD

Section II. Pathophysiology of sleep disordered breathing

Chapter 7. Pathophysiology of Sleep Disordered Breathing in Neonates and Children Sofia Konstantinopoulou, MD and Ignacio E. Tapia, MD

Chapter 8. Pathogenesis of Sleep Disordered Breathing in Adults: Overview Thomas M Tolbert, MD, Indu Ayappa, PhD, David M Rapoport, MD

Chapter 9 Risk and Causality by Genetics, Gender, and Age Moshe Prero, MD, Nardine Zakhary, DO, Sally Ibrahim, MD, Kingman P. Strohl, MD

Chapter 10 The Influence of Cerebral Blood Flow and Cerebrovascular Responsiveness on Ventilatory Control Jay M. J. R. Carr, Gustavo Vizcardo-Galindo, Philip N. Ainslie, PhD Chapter 11 Central Apnea: Propensity and Plasticity MS Badr, MD, MBA Section III. Sleep disordered breathing in different conditions and disease states

Chapter 12 Sleep Disordered Breathing due to Heart Failure Shahrokh Javaheri, MD and R. Germany Chapter 13 Breathing at Altitude David Patz

Chapter 14 Sleep Disordered Breathing associated with Chronic Lung Diseases Bernie Y. Sunwoo MBBS, Ana Sanchez-Azofra MD, Atul Malhotra MD

Chapter 15 Obesity Hypoventilation Syndrome Amanda Piper, PhD

Section 4. Pathophysiology-directed therapies for sleep disordered breathing

Chapter 16 Effect of Positive Airway Pressure on Ventilatory Control and Sleep Disordered Breathing James Rowley, MD

Chapter 17 Mild Intermittent hypoxia and Supplemental Oxygen: Potential therapeutic interventions to treat breathing instability Sreenavya Gandikota, PhD and Jason H. Mateika, Phd

Chapter 18. Pharmacological Management of Sleep Disordered Breathing Thomas J. Altree, Peter G. Catcheside, Sutapa Mukherjee, Danny J. Eckert, PhD

Chapter 19 Neural mechanisms regulating opioid-induced respiratory depression and therapeutic strategies to alleviate the respiratory side-effects of opioid drugs Jean-Philippe Rousseau, Gaspard Montandon, PhD

Chapter 20 Pharmacologic intervention studies to mitigate breathing instability - animal studies Carla Freire, Lenise J Kim, Vsevolod Y. Polotsky PhD