Clinical Biochemistry in Hepatobiliary Diseases

The clinical biochemistry ofhepatobiliary diseases is very widely studied, and publica­ tions abound on this topic. However, there is no recent publication that provides a comprehensive collection of the various leading aspects that go to make up this complex theme. Therefore, we thought it useful to gather together a few scientists whose work has focused on the various clinical biochemistry-aspects of these disorders in order that they might discuss their experience and expertise. The aim of the International Satellite Symposium on Clinical Biochemistry in Hepatobiliary Disease, in addition to reviewing the individual aspects, was to describe the state-of-the-art so as to provide useful data for laboratory scientists and also for physicians working in the field of hepatobiliary diseases, and these two aims are clearly reflected in the chapters of this volume. The volume opens with an introductory chapter that gives a general overview of the various aspects of the clinical biochemistry of these disorders, while the closing chapter deals with an important aspect that deserves to be increasingly emphasized in laboratory medicine, i.e., strategies to integrate information coming from the laboratory to make them more useful for clinical diagnosis.

Contenu

The Clinical Biochemistry of Hepatobiliary Diseases.- The Serum Gamma-glutamyltransferase Isoenzyme System and its Diagnostic Role in Hepatobiliary Disease.- Alkaline Phosphatase in Hepatobiliary Disease.- Enzymatic Profiles of Hepatic Disease Investigated by Alkaline Phosphatase Isoenzymes and Isoforms.- Reference Values and Drug Effects on Hepatic Enzymes.- Plasma Amylase in Pancreatic and Hepatobiliary Disease.- Clinical Significance of Recent Developments in Serum Bilirubins.- Methodological and Clinical Aspects of Bile Acid Analysis in Biological Fluids.- Strategies to Integrate Laboratory Information into the Clinical Diagnosis of Hepatic and Acute Pancreatic Disease.- Author Index Volumes 1-8.