Nutrition and Metabolism: Underlying Mechanisms and Clinical Consequences brings together internationally recognized experts to comprehensively review our current understanding of how nutrition interacts with the genetic substrate as well as environmental-exogenous factors, including physical activity or the lack thereof, to result in insulin resistance and the metabolic syndrome. After presenting the scope of the problem, the first major part of the book is devoted to genetics and pathophysiology, the second part of the book presents the public health perspective of the most prevalent problems associated with nutrition and the metabolic syndrome, whereas the third major part of the book focuses on clinical assessment and management of the main disease states associated with inappropriate nutrition and the metabolic syndrome. Finally, general information useful for both clinicians and researchers alike is presented in the Appendix. Nutrition and Metabolism: Underlying Mechanisms and Clinical Consequences offers the reader an up-to-date and authoritative review of the major scientific and clinical aspects of the overlapping areas between nutrition and metabolism.

Contenu
Scope of the Problem.- Resources.- Genetics and Pathophysiology.- Nutrition and the Metabolic Syndrome: A Twenty-First-Century Epidemic of Obesity and Eating Disorders.- Genes and GeneEnvironment Interactions in the Pathogenesis of Obesity and the Metabolic Syndrome.- Environmental Inputs, Intake of Nutrients, and Endogenous Molecules Contributing to the Regulation of Energy Homeostasis.- Central Integration of Environmental and Endogenous Signals Important in the Regulation of Food Intake and Energy Expenditure.- Public Health Perspective.- Insulin Resistance in States of Energy Excess: Underlying Pathophysiological Concepts.- Targeting Childhood Obesity Through Lifestyle Modification.- Diet and Physical Activity in the Prevention of Obesity.- Diet and Exercise in the Prevention and Management of the Metabolic Syndrome.- Nutrition Recommendations.- Diet and Physical Activity in Cancer Prevention.- Food Guide Pyramids and the 2005 MyPyramid.- Nutrition Recommendations for the General Population: Where Is the Science?.- Nutrition Recommendations and Interventions for Subjects with Cardiovascular Disease.- Clinical Assessment and Management.- Medical Nutrition Therapy in the Treatment of Type 1 and Type 2 Diabetes.- Mediterranean Diet in Disease Prevention: Current Perspectives.- Lifestyle and Pharmacology Approaches for the Treatment of Hypertension and Hyperlipidemia.- Diagnosis, Evaluation, and Medical Management of Obesity and Diabetes.- Surgical Management of Obesity and Postoperative Care.- Long-Term Impact of Weight Loss on Obesity and Obesity-Associated Comorbidities.- Methods for Classifying, Diagnosing, and Monitoring Obesity.- Methods for Classifying, Diagnosing, and Monitoring Type II Diabetes.- Resources.- Major Nutrition Recommendations and Interventionsfor Subjects with Hyperlipidemia, Hypertension, and/or Diabetes.