Case Studies in Ethics and HIV Research

Researchers into HIV/AIDS face a gamut of ethical as well as scientific challenges. By viewing the gathering of data as a reciprocal activity between researchers, participants, and their communities, the expert contributors to Case Studies in Ethics and HIV Research bring these challenges to the fore. Studies from the United States and abroad depict the ongoing balance of risks and benefits while analyzing issues that range from confidentiality and informed consent to conducting studies with minority and other marginalized populations, from dealing with government and other funding agencies to ownership of findings. The book's 25 collaborators offer readers new templates for devising and conducting studies that are valid, meaningful, and morally sound, with critical implications for all research involving human subjects.

Twelve case studies illuminate key ethical issues in HIV research and real-world approaches to addressing them, including:

• Recruiting and selecting study participants.

• Providing proper standards of care to control groups.

• Improving researcher safety in the field.

• Special issues in conducting research: activity-identified populations (e.g., IV drug users), children, cognitively-impaired persons, multiple sites.

• Community outreach in service evaluation.

• Training the new generation of researchers.

Improved study design and methodology, and improved outcomes for participants are important steps on the way to preventing and stopping the spread of AIDS. For professionals in public health research, the collective knowledge of Case Studies in Ethics and HIV Research will help to map out the road ahead.

Auteur

Dr. Loue is known internationally for HIV research with minority communities, as well as research ethics and epidemiology. Dr. Loue has written books focusing on Epidemiology, Disease Prevention, and Sexual Practices.

Earl Pike has been engaged in community-based HIV service and prevention program provision and management for over 20 years, and directs Ohio's largest HIV/AIDS service, education, and advocacy.

Texte du rabat

This important work takes as its subject one of medicine's most pressing arenas of ethical debate. There has been a consistent interest in ethical issues arising in the context of HIV research. Ongoing international and multi-site studies and the continuing search for an HIV vaccine continue to prompt examination of how this research is conducted. Also examined are how participants are engaged in the studies and the obligations of the researchers to individual participants and their communities during the course of and following the conclusion of the research. Each chapter of this book is authored primarily by one of the editors (secondarily by the other) and is accompanied by one to two case studies.

Contenu

Human Rights, International Guidelines, and HIV Research.- U.S. Regulations and HIV-Related Research.- The Informed Consent Process.- Working with Boards and Committees: ECs, DSMBs, CABs.- Researcher-Participant Relations.- Researcher-Community Relations.- Recruiting for HIV-Related Research.- Clinical Trials.- Observational Studies.- Behavioral Intervention Studies.- Ethical Issues in Multicenter/Multisite Studies.- HIV Research with Children.- HIV-Related Research with Cognitively Impaired Persons.- Studies with Minority Populations.- Research in International Settings.- Activity-Defined Populations.- Training the Next Generation of Researchers.- Training Community.