This book represents a comprehensive description and evaluation of the most up-to-date approaches to cancer management. Each chapter, prepared by leading basic researchers and clinicians, provides an in depth description of a specific method for cancer management. The chemotherapy section of the book is updated to include the newest drugs as well as those currently in development. Organized by drug class, this section provides the latest information on most drugs, including their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The biological therapy section of the book provides expanded coverage of the currently used cytokines, vaccines, and cell based therapies of cancer. Full consideration is also given to other modern treatment approaches, such as tyrosine kinase inhibitors, inhibitors of tumor angiogenesis, and the transcatheter management of cancer. Current advances in hyperthermia in cancer treatment, hematologic and nutritional support, bone marrow transplantation, pain management and care of the terminally ill patients with cancer are also presented. In summary, this book provides a comprehensive coverage of the current knowledge on the most innovative, systematic and multidisciplinary approaches to the treatment of patients with cancer.

Contenu
I. CHEMOTHERAPY. 1.Plant-derived natural products as anticancer agents. 2.The Vinca Alkaloids. 3.Taxanes and epothilones in cancer treatment. 4.Alkylating Agents. 5.Anthracyclines and Anthracenediones.6. Topoisomerase I inhibitors. 7.Folate Antagonists in Cancer Treatment. 8.Platinum Complexes for the treatment of cancer. 9. Hormone Therapies for Cancer. 10.Effects of Cancer Chemotherapy on Gonadal Function. 11.Targeting the tumor microenvironment for enhancing chemotherapy in hematologic malignancies. II. BIOLOGICAL THERAPY. 12.Cytokines in the treatment of cancer. 13. Antibody-based therapies for solid tumors. 14.Cancer Vaccines. 15. Adoptive Immunotherapy of Cancer using Autologous Lymphocytes. 16.Oncolytic Virus Therapy for Cancer. III. OTHER. 17. Tyrosine kinase inhibitors. 18.Inhibitors of tumor angiogenesis. 19.Transcatheter Management of Neoplasms. Chapter 20. Tumor Stem Cells: Therapeutic Implications of a Paradigm Shift in Multiple Myeloma. IV.HYPERTHERMIA. 21.Induced hyperthermia in the treatment of cancer. V.SUPPORTING MEASURES. 22.Hematologic Support of the Patient with Malignancy. 23.Current Advances in Bone Marrow Transplantation for Cancer Treatment. 24.Pain management in the cancer patient. 25.Management of Nausea and Vomiting in Cancer Patients. 26.Nurtition in the management of the Cancer Patient. 27.Predictive value of interferon-gamma induced indoleamine 2,3-dioxygenase (IDO) expression in cancer patients.