Essentials of 3D Biofabrication and Translation

Essentials of 3D Biofabrication and Translation discusses the techniques that are making bioprinting a viable alternative in regenerative medicine.

The book runs the gamut of topics related to the subject, including hydrogels and polymers, nanotechnology, toxicity testing, and drug screening platforms, also introducing current applications in the cardiac, skeletal, and nervous systems, and organ construction.

Leaders in clinical medicine and translational science provide a global perspective of the transformative nature of this field, including the use of cells, biomaterials, and macromolecules to create basic building blocks of tissues and organs, all of which are driving the field of biofabrication to transform regenerative medicine.

• Provides a new and versatile method to fabricating living tissue
• Discusses future applications for 3D bioprinting technologies, including use in the cardiac, skeletal, and nervous systems, and organ construction
• Describes current approaches and future challenges for translational science
• Runs the gamut of topics related to the subject, from hydrogels and polymers to nanotechnology, toxicity testing, and drug screening platforms

Auteur

Anthony Atala is the Director of the Wake Forest Institute for Regenerative Medicine, and the W.H. Boyce Professor and Chair of the Department of Urology at Wake Forest University. Dr. Atala is a practicing surgeon and a researcher in the area of regenerative medicine. His current work focuses on growing new human cells, tissues and organs. Dr. Atala works with several journals and serves in various roles, including Editor-in-Chief of Stem Cells- Translational Medicine, Current Stem Cell Research and Therapy, and Therapeutic Advances in Urology; as Associate Editor of Tissue Engineering and Regenerative Medicine, Rejuvenation Research, and Gene Therapy and Regulation; as Executive Board Member or Section Editor of the International Journal of Artificial Organs, Organogenesis, and Current Urology Reports; and as Editorial Board member of Expert Opinion on Biological Therapy, Biomedical Materials, Journal of Tissue Science and Engineering, 3D Printing and Additive Manufacturing, Technology, the Journal of Urology, Recent Patents on Regenerative Medicine, BioMed Central-Urology, Urology, and Current Transplantation Reports. Dr. Atala is a recipient of many awards, including the US Congress funded Christopher Columbus Foundation Award, bestowed on a living American who is currently working on a discovery that will significantly affect society, the World Technology Award in Health and Medicine, presented to individuals achieving significant and lasting progress, the Samuel D. Gross Prize, awarded every 5 years to a national leading surgical researcher by the Philadelphia Academy of Surgery, the Barringer Medal from the American Association of Genitourinary Surgeons for distinguished accomplishments, the Gold Cystoscope award from the American Urological Association for advances in the field, the Ramon Guiteras Award for pioneering research in regenerative medicine and outstanding contributions as a scholar and teacher, the Innovation Award from the Society of Manufacturing Engineers for the creation of synthetic organs, and the Rocovich Gold Medal, awarded to a distinguished scientist who has made a major impact on science toward the understanding of human disease. In 2011 he was elected to the Institute of Medicine of the National Academy of Sciences.

Contenu

Preface

1. Bioprinting Essentials of Cell and Protein Viability

2. Software for Biofabrication

3. Design and Quality Control for Translating 3D Printed Scaffolds

4. Inkjet Bioprinting

5. In vivo and in situ Biofabrication by Laser Assisted Bioprinting

6. Stereolithographic 3D Bioprinting for Biomedical Applications

7. Extrusion Bioprinting

8. Indirect Rapid Prototyping for Tissue Engineering

9. Bioprinting Using Aqueous Two Phase System

10. Bioprinting of Organs for Toxicology Testing

11. High Throughput Screening with Biofabrication Platforms

12. Sensors and Bioprinting for Clinical Translation

13. Polymers for Bioprinting

14. Hydrogels for 3D Bioprinting Applications

15. Bioprinting of Organoids

16. Bioprinting of 3D tissues and Organ Constructs

17. Bioprinting of Bone

18. Bioprinting of Cartilage

19. Biofabrication of Vascular Networks

20. Bioprinting of Blood Vessels

21. Bioprinting of Cardiac Tissues

22. Bioprinting of Skin

23. Bioprinting of Nerve

24. Biofabrication: Industrial Perspective