The newly revised edition of this work provides an up-to-date description of the mechanisms of infection and disease production in a clear and logical manner. Dealing in an integrated manner with all microorganisms, the factors common to all infectious diseases are set out. Molecular biology, pathology, and immunology are brought together to explain how an infectious agent causes disease, and how the body reacts to it.

Attachment to and entry of microorganisms
Events occurring immediately after entry
The encounter of the microbe with the phagocytic cell
The spread of microbes through the body
The immune response to infection
Microbial strategies in relation to the immune response
Mechanisms of cell and tissue damage
Recovery from infection
Failure to eliminate the microbe
Host and microbial factors influencing susceptibility
Vaccines

Auteur

Tony Nash is Emeritus Professor of Infectious Diseases at the University of Edinburgh. He has had a distinguished career i the field of viral pathogenesis in which he has over a 150 publications. He is a Fellow of the Royal Society of Edinburgh and of the Academy of medical sciences of the UK.

Contenu

Preface to Fourth Edition.
Preface to the Third Edition.
Preface to the Second Edition.
Preface to the First Edition.
General Principles.
Attachment to and Entry of Microorganisms into the Body.
Events Occurring Immediately After the Entry of the Microorganism.
The Encounter of the Microbe with the Phagocytic Cell.
The Spread of Microbes through the Body.
The Immune Response to Infection.
Microbial Strategies in Relation to the Immune Response.
Mechanisms of Cell and Tissue Damage.
Recovery from Infection.
Failure to Eliminate Microbe.
Host and Microbial Factors Influencing Susceptibility.
Vaccines.
Appendices.
Conclusions.
Glossary.
Subject Index.