Annual Reports in Organic Synthesis - 1970

Annual Reports in Organic Synthesis-1970 presents an annual review of synthetically useful information that would prove beneficial to nearly all organic chemists, both specialist and nonspecialist in synthesis. It should help relieve some of the information storage burden of the specialist and should aid the nonspecialist who is seeking help with a specific problem to become rapidly aware of recent synthetic advances. In producing this volume the editors abstracted 47 primary chemistry journals, selecting useful synthetic advances. All reactions and methods which are new, synthetically useful, and reasonably general are included. Each entry is comprised primarily of structures accompanied by very few comments. The purpose of this is to aid the reader in rapidly scanning the book.

Chapters I-III are organized by reaction type and constitute the major part of the book. Chapter IV deals with methods of synthesizing heterocyclic systems and concentrates heavily on common, simple systems. Chapter V covers the use of new protecting groups. Chapter VI is divided into two parts and covers those synthetically useful transformations which do not fit easily into the first three chapters. The first part deals only with functional group syntheses. The second part is self-explanatory and involves useful multistep sequences.

Contenu

Preface

Journals Abstracted

I. Carbon-Carbon Bond Forming Reactions

A. Carbon-Carbon Single Bonds (see also: Thermal Reactions 149; Photochemical Reactions 181)

1. Alkylation of Aldehydes and Ketones (see also: Nucleophilic Addition to Electron Deficient Carbon 31)

2. Alkylation of Acids and Esters

3. Alkylation of ß-Dicarbonyl and ß-Cyanocarbonyl Systems

4. Alkylation of Nitriles

5. Other Alkylation Procedures

6. Nucleophilic Addition to Electron Deficient Carbon

7. Other Carbon-Carbon Single Bond Forming Reactions

   B. Carbon-Carbon Double Bonds (see also: Dehydrogenations 226; Reductive Eliminations 253)

8. Wittig-Type Olefination Reactions

9. Eliminations

10. Other Carbon-Carbon Double Bond Forming Reactions

11. Allene Forming Reactions

    C. Carbon-Carbon Triple Bonds

    D. Cyclopropanations

12. Carbene or Carbenoid Addition to a Double Bond

13. Other

    E. Thermal Reactions

14. Cycloadditions

15. Other Thermal Reactions

    F. Aromatic Substitutions Forming a New Carbon-Carbon Bond

16. Friedel-Crafts-Type Reactions

17. Phenol Coupling

18. Other

    G. Photochemical Reactions

19. Enone + Olefin Cycloadditions

20. Photocyclizations

21. Other

22. Reviews

    H. Synthesis via Organometallics

23. Organoalanes

24. Organoboranes

25. Hydrosilylation

26. Coupling Reactions

27. Carbonylations and Decarbonylations

28. Olefin Oligomerizations

29. Metalations

30. Other

31. Reviews

    I. Reviews

II. Oxidations

A. C-O Oxidations

1. Alcohol Ketone, Aldehyde

2. Alcohol Acid, Ester

3. Aldehyde Acid, Ester

   B. C-H Oxidations

4. Allylic C-H Bonds

5. Benzylic C-H Bonds

6. Remote C-H Bonds

7. C-H Bonds a to Oxygen or Nitrogen

8. C-H Bonds a to Carbonyl

9. C-H Bonds a to Sulfur

10. Other

    C. C-Hetero Oxidations Other than C-H and C-O

11. C-N Oxidations

12. Other

    D. Amine Oxidations

    E. Sulfur Oxidations

    F. Oxidative Additions to C-C Multiple Bonds

13. Halohydrin Formation

14. Epoxidation

15. Halogenation

16. Hydroxylation

17. Other

    G. Oxidative Substitution on Aromatic Rings

18. Halogenation

19. Hydroxylation

20. Other

    H. Oxidative Cleavages

21. C-C Single Bonds

22. C-C Multiple Bonds

23. Other

    I. Photosensitized Oxygenation

    J. Dehydrogenation

    K. Phenol Quinone Oxidation

    L. Other Oxidations

    M. New Procedures for Preparing Oxidation Reagents

    N. Reviews

III. Reductions

A. C=O Reductions

1. Ketone, Aldehyde Reductions

2. Acid, Anhydride, Acid Chloride Reductions

3. Ester, Lactone Reductions

4. Amide, Lactam Reductions

   B. C-N Multiple Bond Reductions

5. Oxime Reductions

6. Nitrile Reductions

7. Other

   C. N-O Reductions

   D. C-C Multiple Bond Reductions

8. C=C Reductions

9. C=C Reductions

10. Reduction of Aromatic Rings

    E. Hydrogenolysis of C-Hetero Bonds

11. C-O C-H

12. C-Hal C-H

13. C-S C-H

14. C=O CH2

15. Other

    F. Reductive Eliminations

    G. Reductive Cleavages

    H. Hydroboration (reduction only)

    I. Other Reductions

    J. Reviews

IV. Synthesis of Heterocyclics

A. Aziridines

B. Furans

C. Indoles

D. Lactams

E. Lactones

F. Pyrazoles and Pyrazolines

G. Pyrimidines

H. Pyridines

I. Pyrroles and Pyrrolines

J. Quinolines and Isoquinolines

K. Thiophenes

L. Other Heterocycles with One Heteroatom

M. Other Heterocycles

N. Reviews

V. Protecting Groups

A. O-H Protecting Groups

B. N-H Protecting Groups

C. S-H Protecting Groups

D. Terminal Acetylene Protecting Groups

E. Carboxyl Protecting Groups

F. Ketone, Aldehyde Protecting Groups

G. C=C Protecting Groups

H. Phosphate Protecting Groups

I. Sulfone Protecting Groups

VI. Useful Synthetic Preparations

A. Functional Group Preparations

1. Acids

2. Alcohols (see also: Reduction of Carbonyls 231)

3. Alkyl Halides

4. Amides

5. Amines (see also: Amide Reduction 236; Nitrile Reduction 238)

6. Amino Acids

7. Arynes

8. Carbodiimides

9. Diazoalkanes

10. Disulfides

11. Epoxides (see also: Oxidative Additions to C=C 214)

12. Esters

13. Isocyanates

14. Ketones and Aldehydes (see also: C-O Oxidations 199)

15. ß-Dicarbonyl Compounds

16. Nitriles

17. Nitro Compounds

18. Nucleotides (see also: O-H and Phosphate Protecting Groups 284,293)

19. Peptides (see also: O-H and N-H Protecting Groups 284,285)

20. Phenols (see also: Hydroxylation of Aromatic Rings 220)

21. Vinyl Halides, Vinyl Ethers, and Vinyl Esters

    B. Multistep Synthetic Transformations

22. Ketone Transposition

23. Ring Enlargement

24. Other

VII. Other Completely Miscellaneous Reactions

VIII. Miscellaneous Reviews