Adverse Effects of Engineered Nanomaterials

Adverse Effects of Engineered Nanoparticles: A Disease-Oriented Approach provides a systematic evaluation of representative engineered nanomaterial (ENM) of high volume production and of high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies and the general public need to know about nanosafety. This book, written by leading international experts in nanotoxicology and nanmoedicine, gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers and patients. The beneficial applications, both diagnostic and therapeutic, of ENM are also highlighted. This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, and the clinical and pathological consequences of such exposure in the human population.

• Multi-authored book written by leading US and European experts on nanotoxicology and nanomedicine
• Discusses the health implications and a clinical translation of experimental data in this area
• Takes a schematic, non-exhaustive approach to summarize the most important research data in this field
• Includes a glossary, with a brief explanation of the term and with a reference to where the term or phrase has been used will be included within the book

Contenu

ENGINEERED NANOMATERIALS: HAZARD, EXPOSURE, AND SAFETY ASSESSMENT 1. Interactions with the Human Body - Renato Colognato, Margriet V.D.Z. Park, Peter Wick, Wim H. De Jong 2. Exposure Assessment - Antonio Bergamaschi, Ivo Iavicoli, Kai Savolainen 3. Biomonitoring - Enrico Bergamaschi, Andrea Magrini 4. Critical Evaluation of Toxicity Tests - Maria Dusinska, Elise Rundén-Pran, Sara Correia Carreira, Margaret Saunders 5. Computational Approaches - Vidana Epa, Dave Winkler, Lang Tran 6. Regulation and Legislation - Maureen R. Gwinn, Birgit Sokull-Klüttgen

ENGINEERED NANOMATERIALS: IMPACT ON HUMAN HEALTH 7. Respiratory System - Ken Donaldson, Craig Poland 8. Cardiovascular System - Jennifer B. Raftis , Nicholas L. Mills, Rodger Duffin 9. Neurological System - Sandra Ceccatelli, Giuseppe Bardi 10. Immune System - Diana Boraschi, Albert Duschl 11. Skin - Nancy A. Monteiro-Riviere, Francesca Larese Filon 12. Gastrointestinal Tract - Mark A. Jepson 13. Reproductive Toxicity - Karin Sørig Hougaard, Luisa Campagnolo 14. Genotoxicity and Cancer - Shareen H. Doak, Ying Liu, Chunying Chen

BIOMEDICAL APPLICATIONS OF ENGINEERED NANOMATERIALS 15. Diagnostic Applications - Kai Cheng, Zhen Cheng 16. Therapeutic Applications of Engineered Nanomaterials- Cyrill Bussy, Christoph Alexiou, Robby A. Petros, Andreas Nyström, Laura Methven, Kostas Kostarelos