Advances in Personalized Nanotherapeutics

Health agencies have declared personalized nanomedicine as an important area to investigate novel therapies to combat against targeted diseases with no-side effects. The disease profile varies from patient-to-patient and standard therapies sometime are unsuitable for complete cure. This raises the demand of nanomedicine development. The tunable therapeutic salient features of nanomedicine including site-specific delivery and controlled release of a specific drug according to patient requirement make nanomedicine very special. Such of human compatible personalization is very useful in diseases management required to optimize a therapy for health care. Knowing the potentials of the nanomedicines, significant efforts are being to design and develop nano-enabled therapeutic strategies to cure and monitor diseases contributing to personalized health care. As per state-of-the-art, various approaches have been optimized resulting in development of pharmacologically relevant personalized nanomedicine to combat against diseases with improved efficacy and no adverse effects. In this book, we described the fundamentals nanomedicine, nanotechnology for nanomedicine development, approach of personalized nanomedicine, potential novel nano-carriers for site-specific drug delivery, role of nano-bio-technology for efficient therapeutics, nano-pharmacology, targeted CNS drug delivery, stimuli- responsive drug release, aspects of bioinformatics for diseases management, miniaturized bio-sensing systems for diseases detection with monitoring, and nano-bio-technology for diseases management. The challenges in personalized nano-therapeutics development, possible vision to overcome challenges, and future prospects to promote therapies for clinical application are also discussed in this book. We believe that present book would serve as a platform for new scholars of academia and industries to understand state-of-the-art of nano-bio-technology for therapeutics to plan futureresearch to develop effective personalized nanomedicine against targeted diseases. Our book is a call for experts to explore multidisciplinary research towards developing novel personalized nanomedicines to combat against targeted diseases to personalized health care.

Auteur

Ajeet Kaushik is an Assistant Professor in the Department of Immunology at Florida International University.

Dr. Rahul Dev Jayant (Ph.D.), is a Postdoctoral Research Associate in the Prof. Madhavan Nair lab at the Centre of Personalized Nanomedicine, Department of Immunology of Florida International University.

Résumé

Personalized health care to manage diseases and optimized treatment is crucial for everyone to maintain health quality. Significant efforts have been made to design and develop novel nano-enabling therapeutic strategies to cure and monitor diseases for personalized health care. As state-of-the-art, various strategies have been reported to develop personalized nanomedicine to combat against target diseases with no side effects.

In this book proposal, we are trying to describe fundamentals of personalized nanomedicine, novel nanomaterials for drug delivery, role of nanotechnology for efficient therapeutics approach, nano-pharmacology, targeted CNS drug delivery, stimuli responsive drug release and nanotechnology for diseases management. This book would serve as a platform for new scholars to understand state-of-the-art of nanotechnology for therapeutics and designing their future research to develop effective personalized nanomedicine against targeted diseases.

As ofnow, various studies have been reported to design and develop nanomedicines of higher efficacy but unfortunately, such products are up to laboratory research only and need to be well-tested using pre-clinical or human models. Our book would be a call for experts to explore multidisciplinary research for developing novel and efficient approaches to explore smart efficient nanocarriers for site-specific on-demand controlled drug delivery to combat against targeted diseases to personalized health care.

Contenu

Preface.- Nanomedicine.- Personalized Therapeutics: First take home messages.- Nanotechnology for Therapeutics.- Image-guided therapy for CNS Diseases.- Nanomaterials for Drug Delivery.- Nanoformulations for Therapeutics.- Targeted Drug Delivery for Personalized Cure.- Hydrogels: Stimuli responsive to On-demand drug delivery systems.- On-Demand Controlled Drug Delivery.- CNS Drug Delivery for Diseases Eradication: An Overview.- Bioinformatics for diseases management: a personalized therapeutics prospective.- Nano-enabled sensing platforms for personalized care.- Biosensing Devices for Personalized Healthcare.- Future Prospects and Vision.