A Comprehensive Guide to Core Needle Biopsies of the Breast

Breast cancer remains the leading cause of cancer in women, which makes accurate diagnoses on core needle biopsy (CNB) specimens of vital importance in staging and guiding therapy decisions for patients. The first edition of this multi-authored text written by leaders in the field from major academic medical centers provided a comprehensive guide on diagnostic breast pathology in the core biopsy setting. In addition to in-depth coverage of benign and malignant entities encountered in breast core biopsies, the book provided additional resources to improve diagnostic accuracy such as pattern-based approaches to evaluation, mimickers of breast lesions arising in extra-mammary sites, and pitfalls specific to small tissue samples. In recent years, there have been several notable developments in the field of breast pathology including revisions in AJCC breast cancer staging, updated guidelines in the testing and reporting of ER, PR, and HER2, as well asimplementation of immunotherapy and companion biomarker testing. In addition, several key updates were included in the most recent edition of the WHO Classification of Breast Tumours (2020).

In addition to updates specific to individual breast entities, the second edition provides updates regarding biomarker testing in the primary and metastatic setting, and incorporates newly defined entities and updated definitions of rare tumors in alignment with the WHO Classification of Breast Tumours (2020). Furthermore, this edition addresses the role of CNB in companion biomarker testing for eligibility for immunotherapy in the context of advanced triple-negative breast carcinoma.

Written by leaders in the field and edited by expert breast pathologists, The Second Edition of Comprehensive Guide to Core Needle Biopsies of the Breast is the definitive reference on breast core needle biopsies for practicing pathologists, pathology trainees, oncologists and clinicians of patients with breast disease.

Auteur

Sandra J. Shin, MD

Professor and Chairman

Department of Pathology and Laboratory Medicine

Albany Medical College

Pathologist-in-Chief and Director of Laboratories

Albany Medical Center Hospital

47 New Scotland Avenue, Room F117 MC 81 | Albany, NY 12208

518-262-5461; shins1@amc.edu

Yunn-Yi Chen, MD, PhD

Professor

Director of Immunohistochemistry Laboratory

Department of Pathology

University of California San Francisco

1825 4th Street, Room M-2358

San Francisco, CA 94143

415-353-1613; yunn-yi.chen@ucsf.edu.

Paula S. Ginter, MD

Associate Professor of Pathology and Laboratory Medicine

Weill Cornell Medicine

525 East 68th Street

Starr 1013-B

New York, NY 10065 212-746-4065; psg9003@med.cornell.edu

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