Practical Heterocyclic Chemistry

Auteur

V Balasubramaniyan received hisPh. D in 1964 from (Annamalai University). His post-doctoral training at the University of Notre damein Prof. Pasto's group was followed at the University of Wyoming with Prof Paul Blatz.He had been with MSU, MI (Research Associate, Spring 1983) and UW (Faculty, Summer 1983).

Back in India in 1970, he established the graduate department of chemistry at HPT College, Nashik (University of Pune) and initiated independent research in heterocyclic chemistry supported by the University of Pune, UGC, CSIR, DAE and KVIC, all of India (1970 -1993). He received multiple best teacher awards including the prestigious Prof Narasimhan award for best researcher. Since retirement, he continued his teaching and research as Emeritus Professor at MGV Pharmacy college, and SMBT Pharmacy college in medicinal chemistry focused on biological activities (1996 - current). His publications have appeared in all major journals including Nature,JACS, JOC, Chem. Rev., Photochem . Photobiol., Heterocycles, Tetrahedron, Tetrahedron Letters among others .He is currently a visiting senior faculty with Homi Bhabha Centre For Science Education , Mumbai.

Texte du rabat

Practical Heterocyclic Chemistry: A Lab Manual for Syntheses of Heterocycles delves into the entwined history of heterocyclic chemistry and general organic chemistry, tracing their evolution from the crude isolation and utilization of bioactive natural products to their current pivotal role in enhancing the quality of life for humanity and all living organisms. This evolution has also significantly benefited fields like material sciences. This book provides a concise overview of the enabling technologies and modern toolkits that facilitate complex general organic and heterocyclic syntheses. It emphasizes the importance of safe and sustainable synthesis processes, shaped by the game-changing principles of green chemistry. Readers are also made aware of crucial safety considerations in laboratory practice, including hazard mitigation related to starting materials, products, solvents, catalysts, and lab equipment handling. The book covers the essential laboratory skills needed for experiment design, execution, isolation, purification, and characterization, serving as a valuable resource for modern heterocyclic synthesis in academia and industry, making it a useful asset for graduate students and researchers working with Drug Design.

Contenu

1. Introduction: a brief survey of the evolution of heterocycles from the mystic natural products to their modern role
   
   2. Heterocycles in life and society: appreciation of their vital role
   3. A recap of the basic skills essential for heterocyclic synthesis
   4. Numbering and naming of heterocycles
   5. Toolkits available for synthetic procedures for heterocycles
   6. Experimental procedures for select derivatives (for heterocycles
   7. Syntheses of select heterocycles for real-life applications
   8. The literature of heterocyclic chemistry
      9 to 13: syntheses of heterocycles useful in health sciences, agriculture and material sciences