Tropane Alkaloids

This book covers the current research on the plant-based tropane alkaloids (TA) and TA-bearing plants. The first part includes an overview of tropane alkaloids in context to diversity, biosynthesis and significance. The second part covers aspects of in-vitro and allied interventions in these alkaloids.

TAs belong to one of the world's oldest phytomedicines with their valuable ethno-pharmacological applications. The book compiles scientific ideas, perspectives and challenges in this area. Further, the book attempts to investigate the loopholes in existing methodologies, challenges and possible solutions through well thought-out scientific discussions from various eminent research groups.

This book is of high interest to students and researchers in biotechnology, plant biology and pharmacology. As the TAs are of high commercial medicinal value, this book is also a relevant collection of articles for industry experts.

Sheds light on biogenesis and chemotaxonomic significance of tropane alkaloids Covers commercial aspect of tropane alkaloids Discusses various biotechnological interventions in tropane bearing plants

Auteur
Vikas Srivastava is working as Assistant Professor in the Department of Botany, Central University of Jammu, India. He completed his Ph.D. jointly from Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) and Lucknow University, India. Furthermore, he pursued Postdoc from the National Institute of Plant Genome Research (NIPGR), New Delhi, India. With specialization in various aspects of biotechnology, he has acquired training and experience to carry out research in diverse field of plant biology. He has published many articles in journals/books of international repute and has been working as Principal Investigator for major project sanctioned by University Grant Commission (UGC), New Delhi. He is a recipient of various awards and prestigious fellowships. He delivered several invited lectures in institutes of national repute.

Shakti Mehrotra is Consulting Scientist in the Department of Biotechnology, Institute of Engineering and Technology, Dr. A.P.J. Abdul Kalam Technical University, Lucknow, India. She completed her Ph.D. jointly from CSIR-CIMAP and Lucknow University, India. Furthermore, she pursued Postdoc from the Institute of Engineering and Technology, Lucknow (DBT-PDF) and CSIR-CIMAP (DST Young Scientist). With specialization in various aspects of biotechnology, she has acquired training and experience to carry out research in diverse field of plant biotechnology. She has published many articles in journals/books of national and international repute and worked as Principal Investigator for major projects sanctioned by the Department of Science and Technology (DST) and Department of Biotechnology (DBT), Government of India. She is a recipient of various awards and prestigious fellowships. She delivered several presentations in conferences and workshops and received appreciation.

Sonal Mishra is currently working as Dr. D. S. Kothari-Post Doctoral Fellow (UGC-DSKPDF) at the School of Biotechnology, University of Jammu, India. She has recently completed SERB-National Postdoc Fellowship (SERB-NPDF) as Prinicipal Investigator at School of Biotechnology, University of Jammu, India. Further, she completed her Postdoc at Jawaharlal Nehru University and NIPGR, New Delhi, India. She pursued her Ph.D. jointly from CSIR-CIMAP, Lucknow and Jawaharlal Nehru University, New Delhi. With specialization in various aspects of biotechnology, she has acquired training and experience to carry out research in diverse fields of plant biotechnology and molecular biology. She has published many articles in journals/ books of international repute. She is a recipient of various awards and prestigious fellowships. She presented her work in several seminar and conferences and received appreciation.

Texte du rabat

This book covers the current research on the plant-based tropane alkaloids (TA) and TA-bearing plants. The first part includes an overview of tropane alkaloids in context to diversity, biosynthesis and significance. The second part covers aspects of in-vitro and allied interventions in these alkaloids. TAs belong to one of the world s oldest phytomedicines with their valuable ethno-pharmacological applications. The book compiles scientific ideas, perspectives and challenges in this area. Further, the book attempts to investigate the loopholes in existing methodologies, challenges and possible solutions through well thought-out scientific discussions from various eminent research groups. This book is of high interest to students and researchers in biotechnology, plant biology and pharmacology. As the TAs are of high commercial medicinal value, this book is also a relevant collection of articles for industry experts.

Contenu
Part 1. Tropane Alkaloids: Diversity, Biosynthesis and Significance.- Chapter 1. Plant Tropane Alkaloids (TAs): Chemotaxonomic Significance, Biogenesis and Biotechnological interventions.- Chapter 2. Structure and Function of Enzymes Involved in the Biosynthesis of Tropane Alkaloids.- Chapter 3. Plant tropane alkaloids: Commercial stature and production developments.- Part 2. Tropane Alkaloids: In vitro and allied interventions.- Chapter 4. Involvement of various biotechnological contrivances for tropane alkaloids biosynthesis and applications of tropane alkaloid bearing in vitro cultures.- Chapter 5. Biotechnological Production of Tropane Alkaloids: Contribution of Hairy Root Cultures.- Chapter 6. Production of Tropane Alkaloids (TAs) in plant and in vitro cultures of different ploidy levels.- Chapter 7. Current Progress in Tropane Alkaloids Production by Transgenic and Heterologous gene Expression Approaches.- Chapter 8. Tropane Alkaloid Biosynthesis in Plants: Insights from Transcriptome Analysis.- Chapter 9. Transcription Factor and MicroRNA-mediated Manipulation of the Tropane Alkaloids Biosynthesis.