Transporters as Targets for Drugs

M. Bingham - S. Napier: Overview: Transporters as Targets for Drug Discovery

I. Sylte - A.W. Ravna - G. Sager - S.G. Dahl: Membrane Transporters: Structure, Function and Targets for Drug Design

G.A. Whitlock - M.D. Andrews - A.D. Brown - P.V Fish - A. Stobie - F. Wakehut: Design of Monoamine Reuptake Inhibitors - SSRIs, SNRIs and NRIs

A. Hauck Newman - J.L. Katz: Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter

Z. Chen - J. Yang - P. Skolnick: The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors

G. Antoni - J. Sörensen - H. Hall: Molecular Imaging of Transporters with Positron Emission Tomography

R. Bridges - S.A. Patel: Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System xc

R. Gilfillan - J. Kerr G. - Walker - G. Wishart: Glycine Transporters and Their Inhibitors

In each volume an overview chapter introduces the newcomer to the topic covered Series covers hot topics of frontier research summarized by reputed scientists in the field Review series is topic related Online version available on SpringerLink: springerlink.com Includes supplementary material: sn.pub/extras

Résumé
With contributions by numerous experts

Contenu
Overview: Transporters as Targets for Drug Discovery.- Membrane Transporters: Structure, Function and Targets for Drug Design.- Design of Monoamine Reuptake Inhibitors: SSRIs, SNRIs and NRIs.- Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter.- The Design, Synthesis and StructureActivity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors.- Molecular Imaging of Transporters with Positron Emission Tomography.- Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System x c ?.- Glycine Transporters and Their Inhibitors.