Traditional Resources and Tools for Modern Drug Discovery

This book provides perspectives on the combinatorial approach of plant-based compounds for drug discovery to achieve better disease-curing outcomes introducing the evolution of ethnobotany and traditional medicine in modern drug development. It covers the biotechnological interventions for the identification and screening of compounds and their optimization to enhance affinity, selectivity, bioavailability, and metabolic stability. While overviewing how essential compounds are successfully identified from herbal/ medicinal plants and utilized in the form of effective drugs which eventually have helped in combating long-term diseases in humans, the book also provides a better understanding of how infection and the diseases caused are regulated at the molecular and physiological stages. The book also highlights the importance of bioactive compounds in modern drug discovery and the perspectives for a potential industrial application. The chapters are developed by eminent subject experts with due care and clarity and cover an up-to-date literature review with relevant illustrations. The book would cater to the needs of undergraduate and graduate students, researchers, and scientists, and may attract the attention of pharmaceutical companies/industrialists and health policymakers.

Overviews modern drug discovery research in combinatory of traditional medicine Describes economic aspects of natural products in drug discovery Covers how diseases are regulated at the molecular and physiological stages

Auteur

Anupam Das Talukdar

Professor, Department of Life Science & Bioinformatics, Assam University, India

Prof. Anupam Das Talukdar, M.Sc., Ph.D., currently works as a Professor in the Department of Life Science & Bioinformatics at Assam University, Silchar, Assam, India. With 21 years of teaching and research experience in phytochemistry, structure-based drug design, computer-aided drug discovery, and natural product study, he has excelled in his field. In his current research area, he has successfully completed 6 research projects funded by various national funding agencies of India as a Principal Investigator. Prof. Talukdar has supervised 13 Ph.D. and 5 M.Phil. scholars, and currently 4 Ph.D. scholars are working under his guidance. He has contributed significantly to academia, with more than 95 international research articles, 44 book chapters, and 5 books to his credit.His expertise is recognized internationally, as he serves on the editorial boards and as a reviewer for many esteemed journals. He was awarded gold medals twice during his early academic years for securing the first-class first position in both his Bachelor's and Master's degrees. Additionally, he was honoured with the prestigious DBT - Overseas Associateship for his post-doctoral studies in the UK. Prof. Talukdar earned his Ph.D. degree from Assam University, Silchar, Assam, India, in collaboration with Bose Institute, Kolkata, India.

Jayanta Kumar Patra

Associate Professor, Dongguk University, Republic of Korea

Prof. Dr. Jayanta Kumar Patra, M.Sc., Ph.D., PDF, currently working as Associate Professor at Dongguk University, Republic of Korea. He has about 14 years of research and teaching experience in the field of food, pharmacological and nano-biotechnology. To his credit, he has published more than 180 papers in various national and international peer-reviewed journals and around 40 book chapters in different edited books. Dr. Patra has also authored 20 books in various academic publications.

Gitishree Das

Associate Professor, Dongguk University, Republic of Korea

Prof. Dr. Gitishree Das, M.Sc. Ph.D., PDF, is currently working as Associate Professor at Dongguk University, Republic of Korea. She has 12 years of research experience in the field of rice molecular biology, plant breeding, endophytic bacteria, green nanotechnology. To her credit, she has published around 100 research articles in international and national reputed journals and around 25 book chapters. Dr. Das has also authored 08 books for various international publishers. She is an editorial board member of some national and international journals.

Deepa Nath

Assistant Professor, Dept. of Botany, Gurucharan College, India

Dr. Deepa Nath, MPhil, Ph.D., currently serving as an Assistant Professor in the Department of Botany at Gurucharan College, Silchar, Assam, India. With a robust academic background and post-Ph.D. research experience in phytochemistry, and plant tissue culture, she has made significant contributions to her field. Dr. Nath completed her Ph.D. from the Department of Life Science & Bioinformatics, Assam University, Silchar. She also holds an M.Phil. degree from the same department. Throughout her academic career, Dr. Nath has received recognition for her excellence. She obtained a Gold Medal for securing the first-class first position in M.Sc. (Botany). Dr. Nath has published extensively in reputed international journals and contributed to several book chapters, emphasizing her expertise in phytochemistry and natural product research. With a strong academic foundation and a passion for research, Dr. Deepa Nath continues to make significant strides in the field of phytochemistry and plant biology.

Contenu

Chapter 1. Introduction to ethnobotany and traditional medicine.- Chapter 2. Evolution of traditional resources and their uses in the field of drug discovery: its present-day impact in society.- Chapter 3. Different tools for modern drug discovery research.- Chapter 4. Phytopharmaceutical drugs from traditional resources.- Chapter 5. Importance of traditional knowledge in modern drug discovery.- Chapter 6. The importance of traditional resources in ethnomedicine.- Chapter 7. Role of Ethnomedicinal resources as therapeutic agents in modern drug development.- Chapter 8. Impact of medicinal plants on modern drug discovery.- Chapter 9. Importance of biomarkers from natural resources in modern drug discovery.- Chapter 10. Role of metabolomics from traditional resources in modern drugs.- Chapter 11. Importance of Reverse pharmacology from ethnomedicinal studies in drug discovery.-Chapter 12. Poly-pharmacological approach in the study of ethnomedicinal compounds and drug discovery.-Chapter 13. Nutraceutical approach from natural plant-based resources and their significance in modern drugs.-Chapter 14. The importance of natural products in drug discovery opportunities and success.-Chapter 15. The ethnomedicinal value of traditional medicinal herbs.-Chapter 16. Importance of traditional resources in Pharmacological industries.-Chapter 17. Role of ethnomedicinal resources in curing metabolic diseases.-Chapter 18. Modern drug research and its impact on pharmacological industries.-Chapter 19. Economic benefits of natural products concerning modern drug discovery in the 21st century.-Chapter 20. Economic importance of traditional medicinal resources.-Chapter 21. The market value of traditionally used medicinal plants.